Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus

Mouse models that accurately replicate the immunopathogenesis and clinical disease of alphavirus infection are vital to the preclinical development of therapeutic strategies that target alphavirus infection and disease. Current models rely on subjective scoring made through experienced observation o...

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Main Authors: Eranga Abeyratne, Ronak Reshamwala, Todd Shelper, Xiang Liu, Ali Zaid, Suresh Mahalingam, Adam Taylor
Format: Article
Language:English
Published: American Society for Microbiology 2021-10-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00659-21
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author Eranga Abeyratne
Ronak Reshamwala
Todd Shelper
Xiang Liu
Ali Zaid
Suresh Mahalingam
Adam Taylor
author_facet Eranga Abeyratne
Ronak Reshamwala
Todd Shelper
Xiang Liu
Ali Zaid
Suresh Mahalingam
Adam Taylor
author_sort Eranga Abeyratne
collection DOAJ
description Mouse models that accurately replicate the immunopathogenesis and clinical disease of alphavirus infection are vital to the preclinical development of therapeutic strategies that target alphavirus infection and disease. Current models rely on subjective scoring made through experienced observation of infected mice.
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spelling doaj.art-2b02454a2db945cb97f32ee32c2439b72022-12-21T22:43:24ZengAmerican Society for MicrobiologymSphere2379-50422021-10-016510.1128/mSphere.00659-21Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River VirusEranga Abeyratne0Ronak Reshamwala1Todd Shelper2Xiang Liu3Ali Zaid4Suresh Mahalingam5https://orcid.org/0000-0003-3141-8410Adam Taylor6https://orcid.org/0000-0002-7159-3961Menzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, AustraliaMouse models that accurately replicate the immunopathogenesis and clinical disease of alphavirus infection are vital to the preclinical development of therapeutic strategies that target alphavirus infection and disease. Current models rely on subjective scoring made through experienced observation of infected mice.https://journals.asm.org/doi/10.1128/mSphere.00659-21
spellingShingle Eranga Abeyratne
Ronak Reshamwala
Todd Shelper
Xiang Liu
Ali Zaid
Suresh Mahalingam
Adam Taylor
Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus
mSphere
title Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus
title_full Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus
title_fullStr Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus
title_full_unstemmed Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus
title_short Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus
title_sort altered spatial and temporal gait parameters in mice infected with ross river virus
url https://journals.asm.org/doi/10.1128/mSphere.00659-21
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