Movement Releated Cortical Potentials Obtained by Saccadic Eye Movements In Multiple Sclerosis
Background Movement-related cortical potentials (MRCPs) are electrophysiological activities that reflect neurological mechanisms that occur in the cortex during the planning of and preparation for movement. We aimed to evaluate the MRCPs that occur due to saccadic eye movement in multiple sclerosis...
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| Format: | Article |
| Language: | English |
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Selçuk University
2022-08-01
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| Series: | Genel Tıp Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/2114960 |
| _version_ | 1797686547671154688 |
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| author | Tomris Ugur Egercioglu Zahide Betül Gündüz Osman Serhat Tokgöz Zehra Akpınar |
| author_facet | Tomris Ugur Egercioglu Zahide Betül Gündüz Osman Serhat Tokgöz Zehra Akpınar |
| author_sort | Tomris Ugur Egercioglu |
| collection | DOAJ |
| description | Background
Movement-related cortical potentials (MRCPs) are electrophysiological activities that reflect neurological mechanisms that occur in the cortex during the planning of and preparation for movement. We aimed to evaluate the MRCPs that occur due to saccadic eye movement in multiple sclerosis (MS).
Methods
Twenty-five patients aged 18–55 years with good cognitive functions who were diagnosed with MS according to the McDonald criteria and scored 0–5 on the Expanded Disability Status Scale (EDSS) were included. Twenty healthy volunteers in a similar age range also participated. Voluntary horizontal conjugate gaze and MRCPs were recorded and averaged.
Results
It was observed that the latency of the Bereitshaftpotential (BP; preparation potential) was longer in the patient group, and the latency values were consistent with the values reported in the literature. The peak-pit (PP) amplitude, which can be regarded as a component of the negative slope (NS) and motor potential (MP), was higher in the patient group and may indicate that the target movement was more difficult for the patient group.
Conclusion
Studies on cognitive impairment in MS have generally been conducted using neuropsychological tests. Although we could not obtain a record that corresponded to the typical MRCP pattern reported in the literature, our findings make a contribution to the field of MCRP-based studies by raising new questions about the measurement and use of MRCP values. |
| first_indexed | 2024-03-12T01:06:40Z |
| format | Article |
| id | doaj.art-2b10c4b1b68342aaa4fa9966631eb67f |
| institution | Directory Open Access Journal |
| issn | 2602-3741 |
| language | English |
| last_indexed | 2024-03-12T01:06:40Z |
| publishDate | 2022-08-01 |
| publisher | Selçuk University |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj.art-2b10c4b1b68342aaa4fa9966631eb67f2023-09-14T08:47:58ZengSelçuk UniversityGenel Tıp Dergisi2602-37412022-08-0132323824410.54005/geneltip.1032373154Movement Releated Cortical Potentials Obtained by Saccadic Eye Movements In Multiple SclerosisTomris Ugur Egercioglu0Zahide Betül Gündüz1Osman Serhat Tokgöz2Zehra Akpınar3Selcuklu HospitalSaglik Bilimleri University Konya Sehir HospitalNecmettin Erbakan University Medical FacultyNecmettin Erbakan University Medical FacultyBackground Movement-related cortical potentials (MRCPs) are electrophysiological activities that reflect neurological mechanisms that occur in the cortex during the planning of and preparation for movement. We aimed to evaluate the MRCPs that occur due to saccadic eye movement in multiple sclerosis (MS). Methods Twenty-five patients aged 18–55 years with good cognitive functions who were diagnosed with MS according to the McDonald criteria and scored 0–5 on the Expanded Disability Status Scale (EDSS) were included. Twenty healthy volunteers in a similar age range also participated. Voluntary horizontal conjugate gaze and MRCPs were recorded and averaged. Results It was observed that the latency of the Bereitshaftpotential (BP; preparation potential) was longer in the patient group, and the latency values were consistent with the values reported in the literature. The peak-pit (PP) amplitude, which can be regarded as a component of the negative slope (NS) and motor potential (MP), was higher in the patient group and may indicate that the target movement was more difficult for the patient group. Conclusion Studies on cognitive impairment in MS have generally been conducted using neuropsychological tests. Although we could not obtain a record that corresponded to the typical MRCP pattern reported in the literature, our findings make a contribution to the field of MCRP-based studies by raising new questions about the measurement and use of MRCP values.https://dergipark.org.tr/tr/download/article-file/2114960hareketle ilgili kortikal potansiyellermultipl sklerozsakkadik göz hareketinörolojielektrofizyolojibilişsel bozuklukmovement related cortical potentialsmultiple sclerosissaccadic eye movementneurologyelectrophysiologycognitive impairement |
| spellingShingle | Tomris Ugur Egercioglu Zahide Betül Gündüz Osman Serhat Tokgöz Zehra Akpınar Movement Releated Cortical Potentials Obtained by Saccadic Eye Movements In Multiple Sclerosis Genel Tıp Dergisi hareketle ilgili kortikal potansiyeller multipl skleroz sakkadik göz hareketi nöroloji elektrofizyoloji bilişsel bozukluk movement related cortical potentials multiple sclerosis saccadic eye movement neurology electrophysiology cognitive impairement |
| title | Movement Releated Cortical Potentials Obtained by Saccadic Eye Movements In Multiple Sclerosis |
| title_full | Movement Releated Cortical Potentials Obtained by Saccadic Eye Movements In Multiple Sclerosis |
| title_fullStr | Movement Releated Cortical Potentials Obtained by Saccadic Eye Movements In Multiple Sclerosis |
| title_full_unstemmed | Movement Releated Cortical Potentials Obtained by Saccadic Eye Movements In Multiple Sclerosis |
| title_short | Movement Releated Cortical Potentials Obtained by Saccadic Eye Movements In Multiple Sclerosis |
| title_sort | movement releated cortical potentials obtained by saccadic eye movements in multiple sclerosis |
| topic | hareketle ilgili kortikal potansiyeller multipl skleroz sakkadik göz hareketi nöroloji elektrofizyoloji bilişsel bozukluk movement related cortical potentials multiple sclerosis saccadic eye movement neurology electrophysiology cognitive impairement |
| url | https://dergipark.org.tr/tr/download/article-file/2114960 |
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