Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution
An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-09-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/20/9/17208 |
| _version_ | 1818321397631418368 |
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| author | Xiao-Wei Hong Yu-Qiang Zhou Cui-Bing Bai Nai-Xing Wang Yalan Xing Wei Zhang Yan-Jing Wang Xing-Wang Lan Yu Xie Yi-He Li |
| author_facet | Xiao-Wei Hong Yu-Qiang Zhou Cui-Bing Bai Nai-Xing Wang Yalan Xing Wei Zhang Yan-Jing Wang Xing-Wang Lan Yu Xie Yi-He Li |
| author_sort | Xiao-Wei Hong |
| collection | DOAJ |
| description | An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed. |
| first_indexed | 2024-12-13T10:40:15Z |
| format | Article |
| id | doaj.art-2b12365fbe2b4878a110a580d9cad098 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-13T10:40:15Z |
| publishDate | 2015-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-2b12365fbe2b4878a110a580d9cad0982022-12-21T23:50:33ZengMDPI AGMolecules1420-30492015-09-01209172081722010.3390/molecules200917208molecules200917208Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic ResolutionXiao-Wei Hong0Yu-Qiang Zhou1Cui-Bing Bai2Nai-Xing Wang3Yalan Xing4Wei Zhang5Yan-Jing Wang6Xing-Wang Lan7Yu Xie8Yi-He Li9Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, ChinaTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, ChinaTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, ChinaTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, ChinaDepartment of Chemistry, William Paterson University of New Jersey, 300 Pompton Road, Wayne, NJ 07470, USATechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, ChinaTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, ChinaTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, ChinaCollege of Environment and Chemical Engineering, Nanchang Hangkong University, Nanchang 330063, ChinaTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, ChinaAn efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed.http://www.mdpi.com/1420-3049/20/9/172081,3-oxazolidineasymmetric synthesismulti-component reactionkinetic resolutionsynthetic methods |
| spellingShingle | Xiao-Wei Hong Yu-Qiang Zhou Cui-Bing Bai Nai-Xing Wang Yalan Xing Wei Zhang Yan-Jing Wang Xing-Wang Lan Yu Xie Yi-He Li Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution Molecules 1,3-oxazolidine asymmetric synthesis multi-component reaction kinetic resolution synthetic methods |
| title | Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution |
| title_full | Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution |
| title_fullStr | Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution |
| title_full_unstemmed | Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution |
| title_short | Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution |
| title_sort | asymmetric synthesis of 1 3 oxazolidine derivatives with multi component reaction and research of kinetic resolution |
| topic | 1,3-oxazolidine asymmetric synthesis multi-component reaction kinetic resolution synthetic methods |
| url | http://www.mdpi.com/1420-3049/20/9/17208 |
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