Sirtuin 2 Regulates Microvascular Inflammation during Sepsis
Objective. Sepsis and septic shock, the leading causes of death in noncoronary intensive care units, kill more than 200,000/year in the US alone. Circulating cell-endothelial cell interactions are the rate determining factor in sepsis inflammation. Sirtuin, a seven-member family of proteins (SIRT1–7...
Main Authors: | Nancy Buechler, Xianfeng Wang, Barbara K. Yoza, Charles E. McCall, Vidula Vachharajani |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2017/2648946 |
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