The NLRP3 inflammasome – interleukin 1β axis in uveal melanoma

The NLRP3 inflammasome – interleukin 1β axis in uveal melanoma

Uveal melanoma (UM) is the most common primary intraocular cancer in the adult population. Recent studies suggested that the NLRP3 inflammasome could be a therapeutic target for cutaneous melanoma (CM), but the role of NLRP3 in UM remains unknown. Here, we analyzed the NLRP3‐IL‐1β axis in 5 UM and 4...

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Bibliographic Details
Main Authors: Victor S. M. C. Correa, Nikolaos E. Efstathiou, Dimitrios P. Ntentakis, Zhen Yu, Toshio Narimatsu, Evangelos Gragoudas, Ivana K. Kim, Demetrios G. Vavvas
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:FEBS Open Bio
Subjects:
IL‐1
inflammasome
melanoma
NLRP3
skin
uveal
Online Access:https://doi.org/10.1002/2211-5463.13566

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