Demographic and Survivorship Disparities in Non–muscle-invasive Bladder Cancer in the United States
Objectives To examine survivorship disparities in demographic factors and risk status for non–muscle-invasive bladder cancer (NMIBC), which accounts for more than 75% of all urinary bladder cancers, but is highly curable with early identification and treatment. Methods We used the US National Cancer...
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| Format: | Article |
| Language: | English |
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Korean Society for Preventive Medicine
2018-09-01
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| Series: | Journal of Preventive Medicine and Public Health |
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| Online Access: | http://www.jpmph.org/upload/pdf/jpmph-51-5-242.pdf |
| _version_ | 1819228583138164736 |
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| author | Munseok Seo James R. Langabeer II |
| author_facet | Munseok Seo James R. Langabeer II |
| author_sort | Munseok Seo |
| collection | DOAJ |
| description | Objectives To examine survivorship disparities in demographic factors and risk status for non–muscle-invasive bladder cancer (NMIBC), which accounts for more than 75% of all urinary bladder cancers, but is highly curable with early identification and treatment. Methods We used the US National Cancer Institute’s Surveillance, Epidemiology, and End Results registries over a 19-year period (1988-2006) to examine survivorship disparities in age, sex, race/ethnicity, and marital status of patients and risk status classified by histologic grade, stage, size of tumor, and number of multiple primary tumors among NMIBC patients (n=29 326). We applied Kaplan-Meier (K-M) and Cox proportional hazard methods for survival analysis. Results Among all urinary bladder cancer patients, the majority of NMIBCs were in male (74.1%), non-Latino white (86.7%), married (67.8%), and low-risk (37.6%) to intermediate-risk (44.8%) patients. The mean age was 68 years. Survivorship (in median life years) was highest for non-Latino white (5.4 years), married (5.4 years), and low-risk (5.7 years) patients (K-M analysis, p<0.001). We found significantly lower survivorship for elderly, male (female hazard ratio [HR], 0.96), Latino (HR, 1.20), and unmarried (married HR, 0.93) patients. Conclusions Survivorship disparities were ubiquitous across age, sex, race/ethnicity, and marital status groups. Non-white, unmarried, and elderly patients had significantly shorter survivorship. The implications of these findings include the need for a heightened focus on health policy and more organized efforts to improve access to care in order to increase the chances of survival for all patients. |
| first_indexed | 2024-12-23T10:59:35Z |
| format | Article |
| id | doaj.art-2b181c9735c14b54a50defb10da446ce |
| institution | Directory Open Access Journal |
| issn | 1975-8375 2233-4521 |
| language | English |
| last_indexed | 2024-12-23T10:59:35Z |
| publishDate | 2018-09-01 |
| publisher | Korean Society for Preventive Medicine |
| record_format | Article |
| series | Journal of Preventive Medicine and Public Health |
| spelling | doaj.art-2b181c9735c14b54a50defb10da446ce2022-12-21T17:49:41ZengKorean Society for Preventive MedicineJournal of Preventive Medicine and Public Health1975-83752233-45212018-09-0151524224710.3961/jpmph.18.0921991Demographic and Survivorship Disparities in Non–muscle-invasive Bladder Cancer in the United StatesMunseok Seo0James R. Langabeer II1 School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, USA School of Public Health, University of Texas Health Science Center, Houston, TX, USAObjectives To examine survivorship disparities in demographic factors and risk status for non–muscle-invasive bladder cancer (NMIBC), which accounts for more than 75% of all urinary bladder cancers, but is highly curable with early identification and treatment. Methods We used the US National Cancer Institute’s Surveillance, Epidemiology, and End Results registries over a 19-year period (1988-2006) to examine survivorship disparities in age, sex, race/ethnicity, and marital status of patients and risk status classified by histologic grade, stage, size of tumor, and number of multiple primary tumors among NMIBC patients (n=29 326). We applied Kaplan-Meier (K-M) and Cox proportional hazard methods for survival analysis. Results Among all urinary bladder cancer patients, the majority of NMIBCs were in male (74.1%), non-Latino white (86.7%), married (67.8%), and low-risk (37.6%) to intermediate-risk (44.8%) patients. The mean age was 68 years. Survivorship (in median life years) was highest for non-Latino white (5.4 years), married (5.4 years), and low-risk (5.7 years) patients (K-M analysis, p<0.001). We found significantly lower survivorship for elderly, male (female hazard ratio [HR], 0.96), Latino (HR, 1.20), and unmarried (married HR, 0.93) patients. Conclusions Survivorship disparities were ubiquitous across age, sex, race/ethnicity, and marital status groups. Non-white, unmarried, and elderly patients had significantly shorter survivorship. The implications of these findings include the need for a heightened focus on health policy and more organized efforts to improve access to care in order to increase the chances of survival for all patients.http://www.jpmph.org/upload/pdf/jpmph-51-5-242.pdfRiskUrinary bladder neoplasmsAgedSurvival analysis |
| spellingShingle | Munseok Seo James R. Langabeer II Demographic and Survivorship Disparities in Non–muscle-invasive Bladder Cancer in the United States Journal of Preventive Medicine and Public Health Risk Urinary bladder neoplasms Aged Survival analysis |
| title | Demographic and Survivorship Disparities in Non–muscle-invasive Bladder Cancer in the United States |
| title_full | Demographic and Survivorship Disparities in Non–muscle-invasive Bladder Cancer in the United States |
| title_fullStr | Demographic and Survivorship Disparities in Non–muscle-invasive Bladder Cancer in the United States |
| title_full_unstemmed | Demographic and Survivorship Disparities in Non–muscle-invasive Bladder Cancer in the United States |
| title_short | Demographic and Survivorship Disparities in Non–muscle-invasive Bladder Cancer in the United States |
| title_sort | demographic and survivorship disparities in non muscle invasive bladder cancer in the united states |
| topic | Risk Urinary bladder neoplasms Aged Survival analysis |
| url | http://www.jpmph.org/upload/pdf/jpmph-51-5-242.pdf |
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