Importin 13-dependent axon diameter growth regulates conduction speeds along myelinated CNS axons
Abstract Axon diameter influences the conduction properties of myelinated axons, both directly, and indirectly through effects on myelin. However, we have limited understanding of mechanisms controlling axon diameter growth in the central nervous system, preventing systematic dissection of how manip...
Main Authors: | Jenea M. Bin, Daumante Suminaite, Silvia K. Benito-Kwiecinski, Linde Kegel, Maria Rubio-Brotons, Jason J. Early, Daniel Soong, Matthew R. Livesey, Richard J. Poole, David A. Lyons |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-45908-6 |
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