Systematic Evaluation and Nursing Outlook of Clinical Characteristics of 60 Twin Pregnancies with Complete Hydatidiform Mole and a Coexistent Viable Foetus
Jing Yang,1,* Zhan Shi,1,* Shafeng Jia,1,* Jia Liu,2,* Ling Jiang,2 Yueqin Zhu2 1Department of Obstetrics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, People’s Republic of China; 2Department of Nursing Department, G...
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| Format: | Article |
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Dove Medical Press
2023-10-01
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| Series: | Patient Preference and Adherence |
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| Online Access: | https://www.dovepress.com/systematic-evaluation-and-nursing-outlook-of-clinical-characteristics--peer-reviewed-fulltext-article-PPA |
| _version_ | 1797646902520446976 |
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| author | Yang J Shi Z Jia S Liu J Jiang L Zhu Y |
| author_facet | Yang J Shi Z Jia S Liu J Jiang L Zhu Y |
| author_sort | Yang J |
| collection | DOAJ |
| description | Jing Yang,1,* Zhan Shi,1,* Shafeng Jia,1,* Jia Liu,2,* Ling Jiang,2 Yueqin Zhu2 1Department of Obstetrics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, People’s Republic of China; 2Department of Nursing Department, Gusu School, Nanjing Medical University, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shafeng Jia, Department of Obstetrics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215002, People’s Republic of China, Tel +86-0512-62362039, Email Jiashafeng_1215@163.com Jia Liu, Department of Nursing department, Gusu School, Nanjing Medical University, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215002, People’s Republic of China, No. 26, Daoqian Street, Email Liujia123@email.cnObjective: To analyse the clinical data of and provide a reference for the care and perinatal health care of twin pregnancy patients with complete hydatidiform mole and a coexistent foetus (CHM & CF).Methods: We searched the China National Knowledge Infrastructure (CNKI) and Wanfang and VIP databases to comprehensively collect clinical studies on the “clinical characteristics of complete hydatidiform mole and coexisting foetal twin pregnancy”. Patients’ data were extracted from the literature, and 60 patients were divided into Group A (live newborns not delivered, 47) and Group B (live newborns delivered, 13). The clinical characteristics of the two groups were compared to explore the pregnancy outcomes and influencing factors of persistent gestational trophoblastic disease (pGTD) in patients with CHM & CF.Results: The gestational week of diagnosis (Odd Ratio (OR)=0.203, 95% Confidence Interval (CI)=0.055– 0.753) and number of complications (OR=0.328, 95% CI=0.135– 0.793) were found to be independent influencing factors of pregnancy outcomes in patients with CHM & CF (p < 0.05). Ovulation induction therapy (OR=2.333, 95% CI=0.561– 9.708), preeclampsia (OR=75.000, 95% CI=11.041– 509.486) and the number of complications (OR=4.768, 95% CI=1.914– 11.875) were the independent influencing factors of developing pGTD (p < 0.05).Conclusion: Pregnancy should not be terminated immediately after the early detection of CHM & CF, and multiple factors should be considered. Preeclampsia may indicate a poor prognosis, and ovulation induction may increase the incidence of pGTD. Targeted nursing and psychological nursing should be carried out according to the clinical symptoms of the patients.Keywords: twin pregnancy, complete hydatidiform mole and coexistent foetus, persistent gestational trophoblastic disease, clinical characteristics, nursing |
| first_indexed | 2024-03-11T15:09:33Z |
| format | Article |
| id | doaj.art-2b19c243ac8d43beb9260fc10d009102 |
| institution | Directory Open Access Journal |
| issn | 1177-889X |
| language | English |
| last_indexed | 2024-03-11T15:09:33Z |
| publishDate | 2023-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Patient Preference and Adherence |
| spelling | doaj.art-2b19c243ac8d43beb9260fc10d0091022023-10-29T18:02:23ZengDove Medical PressPatient Preference and Adherence1177-889X2023-10-01Volume 172631264087673Systematic Evaluation and Nursing Outlook of Clinical Characteristics of 60 Twin Pregnancies with Complete Hydatidiform Mole and a Coexistent Viable FoetusYang JShi ZJia SLiu JJiang LZhu YJing Yang,1,* Zhan Shi,1,* Shafeng Jia,1,* Jia Liu,2,* Ling Jiang,2 Yueqin Zhu2 1Department of Obstetrics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, People’s Republic of China; 2Department of Nursing Department, Gusu School, Nanjing Medical University, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shafeng Jia, Department of Obstetrics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215002, People’s Republic of China, Tel +86-0512-62362039, Email Jiashafeng_1215@163.com Jia Liu, Department of Nursing department, Gusu School, Nanjing Medical University, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215002, People’s Republic of China, No. 26, Daoqian Street, Email Liujia123@email.cnObjective: To analyse the clinical data of and provide a reference for the care and perinatal health care of twin pregnancy patients with complete hydatidiform mole and a coexistent foetus (CHM & CF).Methods: We searched the China National Knowledge Infrastructure (CNKI) and Wanfang and VIP databases to comprehensively collect clinical studies on the “clinical characteristics of complete hydatidiform mole and coexisting foetal twin pregnancy”. Patients’ data were extracted from the literature, and 60 patients were divided into Group A (live newborns not delivered, 47) and Group B (live newborns delivered, 13). The clinical characteristics of the two groups were compared to explore the pregnancy outcomes and influencing factors of persistent gestational trophoblastic disease (pGTD) in patients with CHM & CF.Results: The gestational week of diagnosis (Odd Ratio (OR)=0.203, 95% Confidence Interval (CI)=0.055– 0.753) and number of complications (OR=0.328, 95% CI=0.135– 0.793) were found to be independent influencing factors of pregnancy outcomes in patients with CHM & CF (p < 0.05). Ovulation induction therapy (OR=2.333, 95% CI=0.561– 9.708), preeclampsia (OR=75.000, 95% CI=11.041– 509.486) and the number of complications (OR=4.768, 95% CI=1.914– 11.875) were the independent influencing factors of developing pGTD (p < 0.05).Conclusion: Pregnancy should not be terminated immediately after the early detection of CHM & CF, and multiple factors should be considered. Preeclampsia may indicate a poor prognosis, and ovulation induction may increase the incidence of pGTD. Targeted nursing and psychological nursing should be carried out according to the clinical symptoms of the patients.Keywords: twin pregnancy, complete hydatidiform mole and coexistent foetus, persistent gestational trophoblastic disease, clinical characteristics, nursinghttps://www.dovepress.com/systematic-evaluation-and-nursing-outlook-of-clinical-characteristics--peer-reviewed-fulltext-article-PPAtwin pregnancycomplete hydatidiform mole and coexistent foetuspersistent gestational trophoblastic diseaseclinical characteristicsnursing |
| spellingShingle | Yang J Shi Z Jia S Liu J Jiang L Zhu Y Systematic Evaluation and Nursing Outlook of Clinical Characteristics of 60 Twin Pregnancies with Complete Hydatidiform Mole and a Coexistent Viable Foetus Patient Preference and Adherence twin pregnancy complete hydatidiform mole and coexistent foetus persistent gestational trophoblastic disease clinical characteristics nursing |
| title | Systematic Evaluation and Nursing Outlook of Clinical Characteristics of 60 Twin Pregnancies with Complete Hydatidiform Mole and a Coexistent Viable Foetus |
| title_full | Systematic Evaluation and Nursing Outlook of Clinical Characteristics of 60 Twin Pregnancies with Complete Hydatidiform Mole and a Coexistent Viable Foetus |
| title_fullStr | Systematic Evaluation and Nursing Outlook of Clinical Characteristics of 60 Twin Pregnancies with Complete Hydatidiform Mole and a Coexistent Viable Foetus |
| title_full_unstemmed | Systematic Evaluation and Nursing Outlook of Clinical Characteristics of 60 Twin Pregnancies with Complete Hydatidiform Mole and a Coexistent Viable Foetus |
| title_short | Systematic Evaluation and Nursing Outlook of Clinical Characteristics of 60 Twin Pregnancies with Complete Hydatidiform Mole and a Coexistent Viable Foetus |
| title_sort | systematic evaluation and nursing outlook of clinical characteristics of 60 twin pregnancies with complete hydatidiform mole and a coexistent viable foetus |
| topic | twin pregnancy complete hydatidiform mole and coexistent foetus persistent gestational trophoblastic disease clinical characteristics nursing |
| url | https://www.dovepress.com/systematic-evaluation-and-nursing-outlook-of-clinical-characteristics--peer-reviewed-fulltext-article-PPA |
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