A Comparison in Prevalence of Helicobacter pylori in the Gingival Crevicular Fluid from Subjects with Periodontitis and Healthy Individuals using Polymerase Chain Reaction
Background and aims. The high prevalence of Helicobacter pylori among the microorganisms isolated from the oral environment brings up the question of whether oral cavity acts as a reservoir for this bacterium. The aim of the present study was to determine and compare the prevalence of H. pylori in...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2013-12-01
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Series: | Journal of Dental Research, Dental Clinics, Dental Prospects |
Subjects: | |
Online Access: | http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/512/314 |
Summary: | Background and aims. The high prevalence of Helicobacter pylori among the microorganisms isolated from the oral
environment brings up the question of whether oral cavity acts as a reservoir for this bacterium. The aim of the present
study was to determine and compare the prevalence of H. pylori in gingival crevicular fluid (GCF) of patients with chronic
periodontitis (CP) as an infectious disease and healthy subjects using polymerase chain reaction (PCR).
Materials and methods. Periodontal examination was performed for all participants. Two sterilized paper points were
inserted to the maximum depth of the periodontal pockets of selected teeth. The presence of H. pylori was determined by
PCR. In the CP group, the severity of disease was defined as moderate or severe. Further, the frequency of Helicobacter
pylori in GCF of each category, and the association between the presence of Helicobacter pylori in GCF and periodontitis
were determined.
Results. There was no statistically significant association between CP and the presence of H. pylori in the GCF (P = 0.62),
there was no significant correlation between the presence of H. pylori in the GCF and gender of the subjects (P = 0.28 in CP
group and P = 0.25 in control group), and there was no significant correlation between the presence of H. pylori in the GCF
and severity of periodontitis (P = 0.20).
Conclusion. Oral cavity acts as a reservoir for H. pylori; however, the results do not show that H. pylori is involved in
periodontal disease |
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ISSN: | 2008-210X 2008-2118 |