Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature
Abstract Background Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder associated with a broad symptom presentation that is still being characterized. We report a rare case of recurrent mycoplasma skin abscesses in a patient with a history of autoimmune disorders and prol...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-04-01
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| Series: | Allergy, Asthma & Clinical Immunology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13223-022-00673-3 |
| _version_ | 1819045184406552576 |
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| author | David X. Gao Habiba Hussain Brianna Bobber Peter Phan |
| author_facet | David X. Gao Habiba Hussain Brianna Bobber Peter Phan |
| author_sort | David X. Gao |
| collection | DOAJ |
| description | Abstract Background Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder associated with a broad symptom presentation that is still being characterized. We report a rare case of recurrent mycoplasma skin abscesses in a patient with a history of autoimmune disorders and prolonged mycoplasma pneumonia who was diagnosed with CVID. Case presentation A 34-year-old woman presented with a history of recurrent abscesses previously confirmed positive for Mycoplasma pneumoniae. Her past medical history of recurrent mycoplasma abscesses, prolonged mycoplasma pneumonia, and autoimmune disorders (mixed connective tissue disease and immune thrombocytopenia) raised suspicion of CVID. Workup included negative anti-mycoplasma antibody titers, hypogammaglobulinemia, and negative anti-pneumococcal antibody titers despite prior vaccination, solidifying the diagnosis of CVID. The patient was discharged on antibiotic and intravenous immunoglobulin therapy and now follows allergy and immunology long-term for treatment. Conclusions Her diagnostic history underscores the importance of considering the various criteria of CVID for diagnosis, and her unique presentation of M. pneumoniae skin abscesses highlights the broad sequelae patients with CVID can manifest. |
| first_indexed | 2024-12-21T10:24:32Z |
| format | Article |
| id | doaj.art-2b1e2a6aaca348a8a66801d913832e3d |
| institution | Directory Open Access Journal |
| issn | 1710-1492 |
| language | English |
| last_indexed | 2024-12-21T10:24:32Z |
| publishDate | 2022-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Allergy, Asthma & Clinical Immunology |
| spelling | doaj.art-2b1e2a6aaca348a8a66801d913832e3d2022-12-21T19:07:20ZengBMCAllergy, Asthma & Clinical Immunology1710-14922022-04-011811510.1186/s13223-022-00673-3Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literatureDavid X. Gao0Habiba Hussain1Brianna Bobber2Peter Phan3University of Illinois College of MedicineUniversity of Illinois College of MedicineUniversity of Illinois College of MedicineUniversity of Illinois College of MedicineAbstract Background Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder associated with a broad symptom presentation that is still being characterized. We report a rare case of recurrent mycoplasma skin abscesses in a patient with a history of autoimmune disorders and prolonged mycoplasma pneumonia who was diagnosed with CVID. Case presentation A 34-year-old woman presented with a history of recurrent abscesses previously confirmed positive for Mycoplasma pneumoniae. Her past medical history of recurrent mycoplasma abscesses, prolonged mycoplasma pneumonia, and autoimmune disorders (mixed connective tissue disease and immune thrombocytopenia) raised suspicion of CVID. Workup included negative anti-mycoplasma antibody titers, hypogammaglobulinemia, and negative anti-pneumococcal antibody titers despite prior vaccination, solidifying the diagnosis of CVID. The patient was discharged on antibiotic and intravenous immunoglobulin therapy and now follows allergy and immunology long-term for treatment. Conclusions Her diagnostic history underscores the importance of considering the various criteria of CVID for diagnosis, and her unique presentation of M. pneumoniae skin abscesses highlights the broad sequelae patients with CVID can manifest.https://doi.org/10.1186/s13223-022-00673-3Common variable immunodeficiencyMycoplasma |
| spellingShingle | David X. Gao Habiba Hussain Brianna Bobber Peter Phan Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature Allergy, Asthma & Clinical Immunology Common variable immunodeficiency Mycoplasma |
| title | Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature |
| title_full | Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature |
| title_fullStr | Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature |
| title_full_unstemmed | Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature |
| title_short | Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature |
| title_sort | turning walking pneumonia into recurrent abscesses a curious case of cvid and review of the literature |
| topic | Common variable immunodeficiency Mycoplasma |
| url | https://doi.org/10.1186/s13223-022-00673-3 |
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