Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports
Abstract Background Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that predominantly affects young females. Prognosis is excellent; however, 10–15% of patients show metastasis at the time of surgery or develop tumor recurrence after pancreatectomy. Case presentation We reviewed the...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-01-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-022-01358-0 |
| _version_ | 1818752878751252480 |
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| author | Kiyonori Tanoue Yuko Mataki Hiroshi Kurahara Tetsuya Idichi Yota Kawasaki Yoichi Yamasaki Yoshiaki Kita Yuto Hozaka Hideyuki Oi Akihiro Nakajo Takaaki Arigami Kosei Maemura Takao Ohtsuka |
| author_facet | Kiyonori Tanoue Yuko Mataki Hiroshi Kurahara Tetsuya Idichi Yota Kawasaki Yoichi Yamasaki Yoshiaki Kita Yuto Hozaka Hideyuki Oi Akihiro Nakajo Takaaki Arigami Kosei Maemura Takao Ohtsuka |
| author_sort | Kiyonori Tanoue |
| collection | DOAJ |
| description | Abstract Background Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that predominantly affects young females. Prognosis is excellent; however, 10–15% of patients show metastasis at the time of surgery or develop tumor recurrence after pancreatectomy. Case presentation We reviewed the clinical course of three patients with advanced or recurrent SPN and subsequently underwent multidisciplinary treatment at our institution between 2002 and 2019. The primary tumor was resected in all three patients, and metastases were also resected if indicated. Intensive combined therapy, including re-resection, chemotherapy, ablation, arterial chemoembolization, and radiation therapy, allowed all patients to survive for a long time. The literature review showed that resection seems to be more effective than other treatments for metastatic SPN. Conclusions Multidisciplinary treatment, including resection, may improve the prognosis of patients with SPN with recurrence or metastasis. |
| first_indexed | 2024-12-18T04:58:28Z |
| format | Article |
| id | doaj.art-2b1e3791cb3f432286ebb1f352158329 |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-18T04:58:28Z |
| publishDate | 2022-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-2b1e3791cb3f432286ebb1f3521583292022-12-21T21:20:12ZengSpringerOpenSurgical Case Reports2198-77932022-01-01811610.1186/s40792-022-01358-0Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reportsKiyonori Tanoue0Yuko Mataki1Hiroshi Kurahara2Tetsuya Idichi3Yota Kawasaki4Yoichi Yamasaki5Yoshiaki Kita6Yuto Hozaka7Hideyuki Oi8Akihiro Nakajo9Takaaki Arigami10Kosei Maemura11Takao Ohtsuka12Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Onco-Biological Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Kagoshima City HospitalDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesAbstract Background Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that predominantly affects young females. Prognosis is excellent; however, 10–15% of patients show metastasis at the time of surgery or develop tumor recurrence after pancreatectomy. Case presentation We reviewed the clinical course of three patients with advanced or recurrent SPN and subsequently underwent multidisciplinary treatment at our institution between 2002 and 2019. The primary tumor was resected in all three patients, and metastases were also resected if indicated. Intensive combined therapy, including re-resection, chemotherapy, ablation, arterial chemoembolization, and radiation therapy, allowed all patients to survive for a long time. The literature review showed that resection seems to be more effective than other treatments for metastatic SPN. Conclusions Multidisciplinary treatment, including resection, may improve the prognosis of patients with SPN with recurrence or metastasis.https://doi.org/10.1186/s40792-022-01358-0Solid pseudopapillary neoplasmFrantz tumorMalignancyMultidisciplinary treatment |
| spellingShingle | Kiyonori Tanoue Yuko Mataki Hiroshi Kurahara Tetsuya Idichi Yota Kawasaki Yoichi Yamasaki Yoshiaki Kita Yuto Hozaka Hideyuki Oi Akihiro Nakajo Takaaki Arigami Kosei Maemura Takao Ohtsuka Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports Surgical Case Reports Solid pseudopapillary neoplasm Frantz tumor Malignancy Multidisciplinary treatment |
| title | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
| title_full | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
| title_fullStr | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
| title_full_unstemmed | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
| title_short | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
| title_sort | multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas three case reports |
| topic | Solid pseudopapillary neoplasm Frantz tumor Malignancy Multidisciplinary treatment |
| url | https://doi.org/10.1186/s40792-022-01358-0 |
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