Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department
Methemoglobinemia is a complication that develops when ferrous hemoglobin is oxidized to a ferric state. It may be congenital due to structural hemoglobin defects or acquired through causes such as exposure to local anesthetic drugs or intake of toxins. Methemoglobinemia is characterized by cyanosis...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KARE Publishing
2021-01-01
|
| Series: | Southern Clinics of Istanbul Eurasia |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-16362 |
| _version_ | 1797922507326488576 |
|---|---|
| author | Ayşegül Pala Olena Erkun Öner Özdemir Zahir Şehmusoğlu |
| author_facet | Ayşegül Pala Olena Erkun Öner Özdemir Zahir Şehmusoğlu |
| author_sort | Ayşegül Pala |
| collection | DOAJ |
| description | Methemoglobinemia is a complication that develops when ferrous hemoglobin is oxidized to a ferric state. It may be congenital due to structural hemoglobin defects or acquired through causes such as exposure to local anesthetic drugs or intake of toxins. Methemoglobinemia is characterized by cyanosis when the blood level exceeds 10%, and at higher levels it may cause tissue hypoxemia, coma, cardiovascular collapse, or even death. The primary mechanism used to reduce the methemoglobin level in the body is the nicotinamide adenine dinucleotide phosphate-cytochrome b5 reductase pathway. This case report is a presentation of the diagnosis and treatment of prilocaine-induced methemoglobinemia in 2 recently circumcised infants admitted to the pediatric emergency department. |
| first_indexed | 2024-04-10T14:32:30Z |
| format | Article |
| id | doaj.art-2b1e84ca7fc948b09bf45e2a136a32f6 |
| institution | Directory Open Access Journal |
| issn | 2587-0998 |
| language | English |
| last_indexed | 2024-04-10T14:32:30Z |
| publishDate | 2021-01-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Southern Clinics of Istanbul Eurasia |
| spelling | doaj.art-2b1e84ca7fc948b09bf45e2a136a32f62023-02-15T16:08:42ZengKARE PublishingSouthern Clinics of Istanbul Eurasia2587-09982021-01-0131439740010.14744/scie.2020.16362SCIE-16362Methemoglobinemia in Two Infants Brought to the Pediatric Emergency DepartmentAyşegül Pala0Olena Erkun1Öner Özdemir2Zahir Şehmusoğlu3Department of Pediatrics, Sakarya University Training and Research Hospital, Sakarya, TurkeyDepartment of Pediatrics, Sakarya University Training and Research Hospital, Sakarya, TurkeyDepartment of Pediatric Immunology and Allergy Medicine, Sakarya University Faculty of Medicine, Sakarya, TurkeyDepartment of Pediatrics, Sakarya University Training and Research Hospital, Sakarya, TurkeyMethemoglobinemia is a complication that develops when ferrous hemoglobin is oxidized to a ferric state. It may be congenital due to structural hemoglobin defects or acquired through causes such as exposure to local anesthetic drugs or intake of toxins. Methemoglobinemia is characterized by cyanosis when the blood level exceeds 10%, and at higher levels it may cause tissue hypoxemia, coma, cardiovascular collapse, or even death. The primary mechanism used to reduce the methemoglobin level in the body is the nicotinamide adenine dinucleotide phosphate-cytochrome b5 reductase pathway. This case report is a presentation of the diagnosis and treatment of prilocaine-induced methemoglobinemia in 2 recently circumcised infants admitted to the pediatric emergency department.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-16362cyanosismethemoglobinemia; methylene blue; prilocaine. |
| spellingShingle | Ayşegül Pala Olena Erkun Öner Özdemir Zahir Şehmusoğlu Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department Southern Clinics of Istanbul Eurasia cyanosis methemoglobinemia; methylene blue; prilocaine. |
| title | Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department |
| title_full | Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department |
| title_fullStr | Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department |
| title_full_unstemmed | Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department |
| title_short | Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department |
| title_sort | methemoglobinemia in two infants brought to the pediatric emergency department |
| topic | cyanosis methemoglobinemia; methylene blue; prilocaine. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-16362 |
| work_keys_str_mv | AT aysegulpala methemoglobinemiaintwoinfantsbroughttothepediatricemergencydepartment AT olenaerkun methemoglobinemiaintwoinfantsbroughttothepediatricemergencydepartment AT onerozdemir methemoglobinemiaintwoinfantsbroughttothepediatricemergencydepartment AT zahirsehmusoglu methemoglobinemiaintwoinfantsbroughttothepediatricemergencydepartment |