Neutrophil stunning by metoprolol reduces infarct size
Metoprolol is a selective β1 adrenergic receptor blocker that reduces cardiac infarct size and improves cardiac function. The drug is believed to act on cardiomyocytes; however, here the authors show that metoprolol exerts its beneficial effect on infarcted heart by targeting neutrophils and alterin...
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Bibliographic Details
| Main Authors: |
Jaime García-Prieto,
Rocío Villena-Gutiérrez,
Mónica Gómez,
Esther Bernardo,
Andrés Pun-García,
Inés García-Lunar,
Georgiana Crainiciuc,
Rodrigo Fernández-Jiménez,
Vinatha Sreeramkumar,
Rafael Bourio-Martínez,
José M García-Ruiz,
Alfonso Serrano del Valle,
David Sanz-Rosa,
Gonzalo Pizarro,
Antonio Fernández-Ortiz,
Andrés Hidalgo,
Valentín Fuster,
Borja Ibanez |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2017-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms14780
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