Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates
The production of single enantiomers of drug intermediates has become increasingly important in the pharmaceutical industry. Chiral intermediates and fine chemicals are in high demand from both the pharmaceutical and agrochemical industries for the preparation of bulk drug substances and agricultura...
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| Format: | Article |
| Language: | English |
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University of Zagreb Faculty of Food Technology and Biotechnology
2004-01-01
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| Series: | Food Technology and Biotechnology |
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| Online Access: | http://hrcak.srce.hr/file/163397 |
| _version_ | 1797423407225110528 |
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| author | Ramesh N. Patel |
| author_facet | Ramesh N. Patel |
| author_sort | Ramesh N. Patel |
| collection | DOAJ |
| description | The production of single enantiomers of drug intermediates has become increasingly important in the pharmaceutical industry. Chiral intermediates and fine chemicals are in high demand from both the pharmaceutical and agrochemical industries for the preparation of bulk drug substances and agricultural products. The enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enantioselectivities has been demonstrated. In this article, biocatalytic processes are described for the synthesis of chiral pharmaceutical intermediates. |
| first_indexed | 2024-03-09T07:47:41Z |
| format | Article |
| id | doaj.art-2b23eb6729d2464490e0c17b38daa030 |
| institution | Directory Open Access Journal |
| issn | 1330-9862 1334-2606 |
| language | English |
| last_indexed | 2024-03-09T07:47:41Z |
| publishDate | 2004-01-01 |
| publisher | University of Zagreb Faculty of Food Technology and Biotechnology |
| record_format | Article |
| series | Food Technology and Biotechnology |
| spelling | doaj.art-2b23eb6729d2464490e0c17b38daa0302023-12-03T02:42:20ZengUniversity of Zagreb Faculty of Food Technology and BiotechnologyFood Technology and Biotechnology1330-98621334-26062004-01-01424305325Biocatalytic Synthesis of Chiral Pharmaceutical IntermediatesRamesh N. Patel0Process R & D, Bristol-Myers Squibb, New Brunswick, NJ 08903, USAThe production of single enantiomers of drug intermediates has become increasingly important in the pharmaceutical industry. Chiral intermediates and fine chemicals are in high demand from both the pharmaceutical and agrochemical industries for the preparation of bulk drug substances and agricultural products. The enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enantioselectivities has been demonstrated. In this article, biocatalytic processes are described for the synthesis of chiral pharmaceutical intermediates.http://hrcak.srce.hr/file/163397biocatalysischiral intermediatesanticancerantihypertensiveanti-infectiveenantioselective enzymatic de-protection |
| spellingShingle | Ramesh N. Patel Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates Food Technology and Biotechnology biocatalysis chiral intermediates anticancer antihypertensive anti-infective enantioselective enzymatic de-protection |
| title | Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates |
| title_full | Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates |
| title_fullStr | Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates |
| title_full_unstemmed | Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates |
| title_short | Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates |
| title_sort | biocatalytic synthesis of chiral pharmaceutical intermediates |
| topic | biocatalysis chiral intermediates anticancer antihypertensive anti-infective enantioselective enzymatic de-protection |
| url | http://hrcak.srce.hr/file/163397 |
| work_keys_str_mv | AT rameshnpatel biocatalyticsynthesisofchiralpharmaceuticalintermediates |