Competitive Cooperation of Hemagglutinin and Neuraminidase during Influenza A Virus Entry

Competitive Cooperation of Hemagglutinin and Neuraminidase during Influenza A Virus Entry

The hemagglutinin (HA) and neuraminidase (NA) of influenza A virus possess antagonistic activities on interaction with sialic acid (SA), which is the receptor for virus attachment. HA binds SA through its receptor-binding sites, while NA is a receptor-destroying enzyme by removing SAs. The function...

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Bibliographic Details
Main Authors: Ruikun Du, Qinghua Cui, Lijun Rong
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Viruses
Subjects:
influenza A virus
hemagglutinin
neuraminidase
virus entry
Online Access:https://www.mdpi.com/1999-4915/11/5/458

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