MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in ide...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Diseases |
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| Online Access: | https://www.mdpi.com/2079-9721/11/2/77 |
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| author | Zahra Hasanpour Segherlou Lennon Saldarriaga Esaan Azizi Kim-Anh Vo Ramya Reddy Mohammad Reza Hosseini Siyanaki Brandon Lucke-Wold |
| author_facet | Zahra Hasanpour Segherlou Lennon Saldarriaga Esaan Azizi Kim-Anh Vo Ramya Reddy Mohammad Reza Hosseini Siyanaki Brandon Lucke-Wold |
| author_sort | Zahra Hasanpour Segherlou |
| collection | DOAJ |
| description | Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in identifying potential therapeutic agents. One promising target for the diagnosis and prognosis of SAH is circulating microRNAs, which regulate gene expression and are involved in various physiological and pathological processes. In this review, we discuss the potential of microRNAs as a target for diagnosis, treatment, and prognosis in SAH. |
| first_indexed | 2024-03-11T02:34:27Z |
| format | Article |
| id | doaj.art-2b2507113e8d4c10b99b3f840d579b5d |
| institution | Directory Open Access Journal |
| issn | 2079-9721 |
| language | English |
| last_indexed | 2024-03-11T02:34:27Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diseases |
| spelling | doaj.art-2b2507113e8d4c10b99b3f840d579b5d2023-11-18T10:02:04ZengMDPI AGDiseases2079-97212023-05-011127710.3390/diseases11020077MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid HemorrhageZahra Hasanpour Segherlou0Lennon Saldarriaga1Esaan Azizi2Kim-Anh Vo3Ramya Reddy4Mohammad Reza Hosseini Siyanaki5Brandon Lucke-Wold6Department of Neurosurgery, College of Medicine, University of Florida, Gainesville, FL 32661, USACollege of Medicine, University of Florida, Gainesville, FL 32661, USACollege of Medicine, University of Florida, Gainesville, FL 32661, USACollege of Medicine, University of Florida, Gainesville, FL 32661, USACollege of Medicine, University of Florida, Gainesville, FL 32661, USADepartment of Neurosurgery, College of Medicine, University of Florida, Gainesville, FL 32661, USADepartment of Neurosurgery, College of Medicine, University of Florida, Gainesville, FL 32661, USASubarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in identifying potential therapeutic agents. One promising target for the diagnosis and prognosis of SAH is circulating microRNAs, which regulate gene expression and are involved in various physiological and pathological processes. In this review, we discuss the potential of microRNAs as a target for diagnosis, treatment, and prognosis in SAH.https://www.mdpi.com/2079-9721/11/2/77aneurysmal subarachnoid hemorrhagemicroRNAsexosomes |
| spellingShingle | Zahra Hasanpour Segherlou Lennon Saldarriaga Esaan Azizi Kim-Anh Vo Ramya Reddy Mohammad Reza Hosseini Siyanaki Brandon Lucke-Wold MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage Diseases aneurysmal subarachnoid hemorrhage microRNAs exosomes |
| title | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
| title_full | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
| title_fullStr | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
| title_full_unstemmed | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
| title_short | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
| title_sort | micrornas role in diagnosis and treatment of subarachnoid hemorrhage |
| topic | aneurysmal subarachnoid hemorrhage microRNAs exosomes |
| url | https://www.mdpi.com/2079-9721/11/2/77 |
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