A randomized clinical pharmacokinetic trial of Tenofovir in blood, plasma and urine in adults with perfect, moderate and low PrEP adherence: the TARGET study

A randomized clinical pharmacokinetic trial of Tenofovir in blood, plasma and urine in adults with perfect, moderate and low PrEP adherence: the TARGET study

Abstract Background Tenofovir disoproxil fumarate (TDF) is key component of pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) for HIV, but existing tools to monitor drug adherence are often inaccurate. Detection of tenofovir (TFV) in accessible biological samples, such as fingerprick...

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Bibliographic Details
Main Authors: Tim R. Cressey, Oraphan Siriprakaisil, Virat Klinbuayaem, Justice Quame-Amaglo, Rachel W. Kubiak, Pra-ornsuda Sukrakanchana, Kanchana Than-in-at, Jared Baeten, Wasna Sirirungsi, Ratchada Cressey, Paul K. Drain
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Infectious Diseases
Subjects:
HIV
Pre-exposure prophylaxis
Antiretroviral treatment
Tenofovir
Thailand
Online Access:http://link.springer.com/article/10.1186/s12879-017-2593-4

Internet

http://link.springer.com/article/10.1186/s12879-017-2593-4

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