Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
A novel electrochemical sensor for the selective and sensitive detection of carbidopa in presence of large excess of folic acid at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with carbon nanotubes (CNTs) and vinylferrocene. Large peak separation,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Serbian Chemical Society
2015-01-01
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| Series: | Journal of the Serbian Chemical Society |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400046K.pdf |
| Summary: | A novel electrochemical sensor for the selective and sensitive detection of
carbidopa in presence of large excess of folic acid at physiological pH was
developed by the bulk modification of carbon paste electrode (CPE) with
carbon nanotubes (CNTs) and vinylferrocene. Large peak separation, good
sensitivity and stability allow this modified electrode to analyze carbidopa
individually and simultaneously along with folic acid. Applying square wave
voltammetry (SWV), a linear dynamic range of 1.0×10-6- 7.0×10-4 M with
detection limit of 2.0×10-7 M was obtained for carbidopa. Finally, the
proposed method was applied to the determination of carbidopa and folic acid
in urine sample. |
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| ISSN: | 0352-5139 1820-7421 |