Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode

A novel electrochemical sensor for the selective and sensitive detection of carbidopa in presence of large excess of folic acid at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with carbon nanotubes (CNTs) and vinylferrocene. Large peak separation,...

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Main Authors: Keshtkar Nasrin, Taher Ali Mohammad, Beitollahi Hadi
Format: Article
Language:English
Published: Serbian Chemical Society 2015-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400046K.pdf
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author Keshtkar Nasrin
Taher Ali Mohammad
Beitollahi Hadi
author_facet Keshtkar Nasrin
Taher Ali Mohammad
Beitollahi Hadi
author_sort Keshtkar Nasrin
collection DOAJ
description A novel electrochemical sensor for the selective and sensitive detection of carbidopa in presence of large excess of folic acid at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with carbon nanotubes (CNTs) and vinylferrocene. Large peak separation, good sensitivity and stability allow this modified electrode to analyze carbidopa individually and simultaneously along with folic acid. Applying square wave voltammetry (SWV), a linear dynamic range of 1.0×10-6- 7.0×10-4 M with detection limit of 2.0×10-7 M was obtained for carbidopa. Finally, the proposed method was applied to the determination of carbidopa and folic acid in urine sample.
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spelling doaj.art-2b30bc05664b408fad5e7223ad6ab4d82022-12-22T01:21:48ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51391820-74212015-01-0180678979910.2298/JSC131216046K0352-51391400046KVoltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrodeKeshtkar Nasrin0Taher Ali Mohammad1Beitollahi Hadi2Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran + Young Researchers Society, Shahid Bahonar University of Kerman, Kerman, IranDepartment of Chemistry, Shahid Bahonar University of Kerman, Kerman, IranEnvironment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, IranA novel electrochemical sensor for the selective and sensitive detection of carbidopa in presence of large excess of folic acid at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with carbon nanotubes (CNTs) and vinylferrocene. Large peak separation, good sensitivity and stability allow this modified electrode to analyze carbidopa individually and simultaneously along with folic acid. Applying square wave voltammetry (SWV), a linear dynamic range of 1.0×10-6- 7.0×10-4 M with detection limit of 2.0×10-7 M was obtained for carbidopa. Finally, the proposed method was applied to the determination of carbidopa and folic acid in urine sample.http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400046K.pdfcarbidopafolic acidcarbon nanotubesmodified electrodes
spellingShingle Keshtkar Nasrin
Taher Ali Mohammad
Beitollahi Hadi
Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
Journal of the Serbian Chemical Society
carbidopa
folic acid
carbon nanotubes
modified electrodes
title Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
title_full Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
title_fullStr Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
title_full_unstemmed Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
title_short Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
title_sort voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
topic carbidopa
folic acid
carbon nanotubes
modified electrodes
url http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400046K.pdf
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AT taheralimohammad voltammetricdeterminationofcarbidopaandfolicacidusingamodifiedcarbonnanotubespasteelectrode
AT beitollahihadi voltammetricdeterminationofcarbidopaandfolicacidusingamodifiedcarbonnanotubespasteelectrode