Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode
A novel electrochemical sensor for the selective and sensitive detection of carbidopa in presence of large excess of folic acid at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with carbon nanotubes (CNTs) and vinylferrocene. Large peak separation,...
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Format: | Article |
Language: | English |
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Serbian Chemical Society
2015-01-01
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Series: | Journal of the Serbian Chemical Society |
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Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400046K.pdf |
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author | Keshtkar Nasrin Taher Ali Mohammad Beitollahi Hadi |
author_facet | Keshtkar Nasrin Taher Ali Mohammad Beitollahi Hadi |
author_sort | Keshtkar Nasrin |
collection | DOAJ |
description | A novel electrochemical sensor for the selective and sensitive detection of
carbidopa in presence of large excess of folic acid at physiological pH was
developed by the bulk modification of carbon paste electrode (CPE) with
carbon nanotubes (CNTs) and vinylferrocene. Large peak separation, good
sensitivity and stability allow this modified electrode to analyze carbidopa
individually and simultaneously along with folic acid. Applying square wave
voltammetry (SWV), a linear dynamic range of 1.0×10-6- 7.0×10-4 M with
detection limit of 2.0×10-7 M was obtained for carbidopa. Finally, the
proposed method was applied to the determination of carbidopa and folic acid
in urine sample. |
first_indexed | 2024-12-11T03:55:24Z |
format | Article |
id | doaj.art-2b30bc05664b408fad5e7223ad6ab4d8 |
institution | Directory Open Access Journal |
issn | 0352-5139 1820-7421 |
language | English |
last_indexed | 2024-12-11T03:55:24Z |
publishDate | 2015-01-01 |
publisher | Serbian Chemical Society |
record_format | Article |
series | Journal of the Serbian Chemical Society |
spelling | doaj.art-2b30bc05664b408fad5e7223ad6ab4d82022-12-22T01:21:48ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51391820-74212015-01-0180678979910.2298/JSC131216046K0352-51391400046KVoltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrodeKeshtkar Nasrin0Taher Ali Mohammad1Beitollahi Hadi2Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran + Young Researchers Society, Shahid Bahonar University of Kerman, Kerman, IranDepartment of Chemistry, Shahid Bahonar University of Kerman, Kerman, IranEnvironment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, IranA novel electrochemical sensor for the selective and sensitive detection of carbidopa in presence of large excess of folic acid at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with carbon nanotubes (CNTs) and vinylferrocene. Large peak separation, good sensitivity and stability allow this modified electrode to analyze carbidopa individually and simultaneously along with folic acid. Applying square wave voltammetry (SWV), a linear dynamic range of 1.0×10-6- 7.0×10-4 M with detection limit of 2.0×10-7 M was obtained for carbidopa. Finally, the proposed method was applied to the determination of carbidopa and folic acid in urine sample.http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400046K.pdfcarbidopafolic acidcarbon nanotubesmodified electrodes |
spellingShingle | Keshtkar Nasrin Taher Ali Mohammad Beitollahi Hadi Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode Journal of the Serbian Chemical Society carbidopa folic acid carbon nanotubes modified electrodes |
title | Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode |
title_full | Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode |
title_fullStr | Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode |
title_full_unstemmed | Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode |
title_short | Voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode |
title_sort | voltammetric determination of carbidopa and folic acid using a modified carbon nanotubes paste electrode |
topic | carbidopa folic acid carbon nanotubes modified electrodes |
url | http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400046K.pdf |
work_keys_str_mv | AT keshtkarnasrin voltammetricdeterminationofcarbidopaandfolicacidusingamodifiedcarbonnanotubespasteelectrode AT taheralimohammad voltammetricdeterminationofcarbidopaandfolicacidusingamodifiedcarbonnanotubespasteelectrode AT beitollahihadi voltammetricdeterminationofcarbidopaandfolicacidusingamodifiedcarbonnanotubespasteelectrode |