The need for COVID-19 research in low- and middle-income countries

Abstract In the early months of the pandemic, most reported cases and deaths due to COVID-19 occurred in high-income countries. However, insufficient testing could have led to an underestimation of true infections in many low- and middle-income countries. As confirmed cases increase, the ultimate im...

Full description

Bibliographic Details
Main Authors: Madhu Gupta, Brian Wahl, Binita Adhikari, Naor Bar-Zeev, Sudip Bhandari, Alexandra Coria, Daniel J. Erchick, Nidhi Gupta, Shreya Hariyani, E. Wangeci Kagucia, Japhet Killewo, Rupali Jayant Limaye, Eric D. McCollum, Raghukul Pandey, William S. Pomat, Krishna D. Rao, Mathuram Santosham, Molly Sauer, Rhoda K. Wanyenze, David H. Peters
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Global Health Research and Policy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41256-020-00159-y
_version_ 1819206417421172736
author Madhu Gupta
Brian Wahl
Binita Adhikari
Naor Bar-Zeev
Sudip Bhandari
Alexandra Coria
Daniel J. Erchick
Nidhi Gupta
Shreya Hariyani
E. Wangeci Kagucia
Japhet Killewo
Rupali Jayant Limaye
Eric D. McCollum
Raghukul Pandey
William S. Pomat
Krishna D. Rao
Mathuram Santosham
Molly Sauer
Rhoda K. Wanyenze
David H. Peters
author_facet Madhu Gupta
Brian Wahl
Binita Adhikari
Naor Bar-Zeev
Sudip Bhandari
Alexandra Coria
Daniel J. Erchick
Nidhi Gupta
Shreya Hariyani
E. Wangeci Kagucia
Japhet Killewo
Rupali Jayant Limaye
Eric D. McCollum
Raghukul Pandey
William S. Pomat
Krishna D. Rao
Mathuram Santosham
Molly Sauer
Rhoda K. Wanyenze
David H. Peters
author_sort Madhu Gupta
collection DOAJ
description Abstract In the early months of the pandemic, most reported cases and deaths due to COVID-19 occurred in high-income countries. However, insufficient testing could have led to an underestimation of true infections in many low- and middle-income countries. As confirmed cases increase, the ultimate impact of the pandemic on individuals and communities in low- and middle-income countries is uncertain. We therefore propose research in three broad areas as urgently needed to inform responses in low- and middle-income countries: transmission patterns of SARS-CoV-2, the clinical characteristics of the disease, and the impact of pandemic prevention and response measures. Answering these questions will require a multidisciplinary approach led by local investigators and in some cases additional resources. Targeted research activities should be done to help mitigate the potential burden of COVID-19 in low- and middle-income countries without diverting the limited human resources, funding, or medical supplies from response activities.
first_indexed 2024-12-23T05:07:16Z
format Article
id doaj.art-2b376b8bb3f5405c856148a0c4a1338f
institution Directory Open Access Journal
issn 2397-0642
language English
last_indexed 2024-12-23T05:07:16Z
publishDate 2020-07-01
publisher BMC
record_format Article
series Global Health Research and Policy
spelling doaj.art-2b376b8bb3f5405c856148a0c4a1338f2022-12-21T17:59:02ZengBMCGlobal Health Research and Policy2397-06422020-07-01511410.1186/s41256-020-00159-yThe need for COVID-19 research in low- and middle-income countriesMadhu Gupta0Brian Wahl1Binita Adhikari2Naor Bar-Zeev3Sudip Bhandari4Alexandra Coria5Daniel J. Erchick6Nidhi Gupta7Shreya Hariyani8E. Wangeci Kagucia9Japhet Killewo10Rupali Jayant Limaye11Eric D. McCollum12Raghukul Pandey13William S. Pomat14Krishna D. Rao15Mathuram Santosham16Molly Sauer17Rhoda K. Wanyenze18David H. Peters19Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and ResearchDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthMaimonides Medical CenterDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthEpidemiology and Demography Department, KEMRI-Wellcome Trust Research ProgrammeMuhimbili University of Health and Allied SciencesDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthPapua New Guinea Institute of Medical ResearchDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthMakerere University School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthAbstract In the early months of the pandemic, most reported cases and deaths due to COVID-19 occurred in high-income countries. However, insufficient testing could have led to an underestimation of true infections in many low- and middle-income countries. As confirmed cases increase, the ultimate impact of the pandemic on individuals and communities in low- and middle-income countries is uncertain. We therefore propose research in three broad areas as urgently needed to inform responses in low- and middle-income countries: transmission patterns of SARS-CoV-2, the clinical characteristics of the disease, and the impact of pandemic prevention and response measures. Answering these questions will require a multidisciplinary approach led by local investigators and in some cases additional resources. Targeted research activities should be done to help mitigate the potential burden of COVID-19 in low- and middle-income countries without diverting the limited human resources, funding, or medical supplies from response activities.http://link.springer.com/article/10.1186/s41256-020-00159-yCOVID-19Research agendaGlobal health
spellingShingle Madhu Gupta
Brian Wahl
Binita Adhikari
Naor Bar-Zeev
Sudip Bhandari
Alexandra Coria
Daniel J. Erchick
Nidhi Gupta
Shreya Hariyani
E. Wangeci Kagucia
Japhet Killewo
Rupali Jayant Limaye
Eric D. McCollum
Raghukul Pandey
William S. Pomat
Krishna D. Rao
Mathuram Santosham
Molly Sauer
Rhoda K. Wanyenze
David H. Peters
The need for COVID-19 research in low- and middle-income countries
Global Health Research and Policy
COVID-19
Research agenda
Global health
title The need for COVID-19 research in low- and middle-income countries
title_full The need for COVID-19 research in low- and middle-income countries
title_fullStr The need for COVID-19 research in low- and middle-income countries
title_full_unstemmed The need for COVID-19 research in low- and middle-income countries
title_short The need for COVID-19 research in low- and middle-income countries
title_sort need for covid 19 research in low and middle income countries
topic COVID-19
Research agenda
Global health
url http://link.springer.com/article/10.1186/s41256-020-00159-y
work_keys_str_mv AT madhugupta theneedforcovid19researchinlowandmiddleincomecountries
AT brianwahl theneedforcovid19researchinlowandmiddleincomecountries
AT binitaadhikari theneedforcovid19researchinlowandmiddleincomecountries
AT naorbarzeev theneedforcovid19researchinlowandmiddleincomecountries
AT sudipbhandari theneedforcovid19researchinlowandmiddleincomecountries
AT alexandracoria theneedforcovid19researchinlowandmiddleincomecountries
AT danieljerchick theneedforcovid19researchinlowandmiddleincomecountries
AT nidhigupta theneedforcovid19researchinlowandmiddleincomecountries
AT shreyahariyani theneedforcovid19researchinlowandmiddleincomecountries
AT ewangecikagucia theneedforcovid19researchinlowandmiddleincomecountries
AT japhetkillewo theneedforcovid19researchinlowandmiddleincomecountries
AT rupalijayantlimaye theneedforcovid19researchinlowandmiddleincomecountries
AT ericdmccollum theneedforcovid19researchinlowandmiddleincomecountries
AT raghukulpandey theneedforcovid19researchinlowandmiddleincomecountries
AT williamspomat theneedforcovid19researchinlowandmiddleincomecountries
AT krishnadrao theneedforcovid19researchinlowandmiddleincomecountries
AT mathuramsantosham theneedforcovid19researchinlowandmiddleincomecountries
AT mollysauer theneedforcovid19researchinlowandmiddleincomecountries
AT rhodakwanyenze theneedforcovid19researchinlowandmiddleincomecountries
AT davidhpeters theneedforcovid19researchinlowandmiddleincomecountries
AT madhugupta needforcovid19researchinlowandmiddleincomecountries
AT brianwahl needforcovid19researchinlowandmiddleincomecountries
AT binitaadhikari needforcovid19researchinlowandmiddleincomecountries
AT naorbarzeev needforcovid19researchinlowandmiddleincomecountries
AT sudipbhandari needforcovid19researchinlowandmiddleincomecountries
AT alexandracoria needforcovid19researchinlowandmiddleincomecountries
AT danieljerchick needforcovid19researchinlowandmiddleincomecountries
AT nidhigupta needforcovid19researchinlowandmiddleincomecountries
AT shreyahariyani needforcovid19researchinlowandmiddleincomecountries
AT ewangecikagucia needforcovid19researchinlowandmiddleincomecountries
AT japhetkillewo needforcovid19researchinlowandmiddleincomecountries
AT rupalijayantlimaye needforcovid19researchinlowandmiddleincomecountries
AT ericdmccollum needforcovid19researchinlowandmiddleincomecountries
AT raghukulpandey needforcovid19researchinlowandmiddleincomecountries
AT williamspomat needforcovid19researchinlowandmiddleincomecountries
AT krishnadrao needforcovid19researchinlowandmiddleincomecountries
AT mathuramsantosham needforcovid19researchinlowandmiddleincomecountries
AT mollysauer needforcovid19researchinlowandmiddleincomecountries
AT rhodakwanyenze needforcovid19researchinlowandmiddleincomecountries
AT davidhpeters needforcovid19researchinlowandmiddleincomecountries