Brugada-Type Electrocardiogram in the Taiwanese Population–Is it a Risk Factor for Sudden Death?

People receive electrocardiogram (ECG) examination for various reasons in a hospital setting. An important clinical practice issue may be that cardiologists need to be consulted for Brugada-type ECGs identified through routine screening. We investigated the prevalence and prognosis of patients with...

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Main Authors: Jyh-Ming Jimmy Juang, Wei-Lian Phan, Pau-Chung Chen, Ling-Ping Lai, Min-Hsi Tsai, Jou-Wei Lin, Pi-Hsun Cheng, Wei-Yih Chiu, Bor-Wen Cheng, Juey-Jen Hwang, Chuen-Den Tseng, Kwan-Lih Hsu, Yung-Zu Tseng, Jiunn-Lee Lin, Fu-Tien Chiang
Format: Article
Language:English
Published: Elsevier 2011-04-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664611600351
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author Jyh-Ming Jimmy Juang
Wei-Lian Phan
Pau-Chung Chen
Ling-Ping Lai
Min-Hsi Tsai
Jou-Wei Lin
Pi-Hsun Cheng
Wei-Yih Chiu
Bor-Wen Cheng
Juey-Jen Hwang
Chuen-Den Tseng
Kwan-Lih Hsu
Yung-Zu Tseng
Jiunn-Lee Lin
Fu-Tien Chiang
author_facet Jyh-Ming Jimmy Juang
Wei-Lian Phan
Pau-Chung Chen
Ling-Ping Lai
Min-Hsi Tsai
Jou-Wei Lin
Pi-Hsun Cheng
Wei-Yih Chiu
Bor-Wen Cheng
Juey-Jen Hwang
Chuen-Den Tseng
Kwan-Lih Hsu
Yung-Zu Tseng
Jiunn-Lee Lin
Fu-Tien Chiang
author_sort Jyh-Ming Jimmy Juang
collection DOAJ
description People receive electrocardiogram (ECG) examination for various reasons in a hospital setting. An important clinical practice issue may be that cardiologists need to be consulted for Brugada-type ECGs identified through routine screening. We investigated the prevalence and prognosis of patients with Brugadatype ECG in a hospital-based population in an attempt to improve the management of these patients. Methods: In 20,562 patients seeking medical care for non-cardiovascular reasons, 74,955 ECGs were performed from December 1999 to February 2001. The diagnostic criteria for Brugada-like ECG from the European Society of Cardiology were used. International Statistical Classification of Diseases codes and city residents' records were documented to indicate the reasons for visiting clinics or hospitalization and mortality outcome. Medical records were reviewed and telephone interviews were conducted. Results: Twenty-six (0.13%) of the 20,562 patients were confirmed to have Brugada-type ECGs. None of these patients had ever experienced syncope, near syncope or sudden cardiac death. After 57.1 ± 15.8 months of follow-up, there were four deaths out of the 26 patients with Brugada-type ECG (15.4%, 95% CI: 1.53-2.9%) compared with 2899 of those without (14.1%, 95% CI: 13.6-14.5%; p=0.89, log-rank test). Neither sudden cardiac death (p=0.61) nor hospitalized death (p=0.55) was different between patients with and without Brugada-type ECG. Conclusion: Patients with Brugada-type ECGs are not rare in a hospital-based population. The presence of Brugada-type ECGs in patients without syncope or sudden cardiac death was not associated with hospitalized mortality.
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spelling doaj.art-2b3b415da1fc4c91986fb1dc9e517ce52022-12-21T20:13:54ZengElsevierJournal of the Formosan Medical Association0929-66462011-04-01110423023810.1016/S0929-6646(11)60035-1Brugada-Type Electrocardiogram in the Taiwanese Population–Is it a Risk Factor for Sudden Death?Jyh-Ming Jimmy Juang0Wei-Lian Phan1Pau-Chung Chen2Ling-Ping Lai3Min-Hsi Tsai4Jou-Wei Lin5Pi-Hsun Cheng6Wei-Yih Chiu7Bor-Wen Cheng8Juey-Jen Hwang9Chuen-Den Tseng10Kwan-Lih Hsu11Yung-Zu Tseng12Jiunn-Lee Lin13Fu-Tien Chiang14Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanDivision of Cardiology, Departments of Internal Medicine, Li Shin Hospital, Taoyuan County, TaiwanInstitute of Occupational Medicine & Industrial Hygiene, National Taiwan University College of Public Health, National Taiwan University, Taipei; TaiwanDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanDivision of Biostatistics, Graduate institute of Epidemiology, College of Public Health, National Taiwan University, Taipei; TaiwanDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanDepartment of Industrial Engineering and Management, National Yunlin University of Science and Technology, Yun-Lin County, TaiwanDepartment of Internal Medicine, En-Chu-Kong Hospital, Taipei County, TaiwanDepartment of Industrial Engineering and Management, National Yunlin University of Science and Technology, Yun-Lin County, TaiwanDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei; TaiwanPeople receive electrocardiogram (ECG) examination for various reasons in a hospital setting. An important clinical practice issue may be that cardiologists need to be consulted for Brugada-type ECGs identified through routine screening. We investigated the prevalence and prognosis of patients with Brugadatype ECG in a hospital-based population in an attempt to improve the management of these patients. Methods: In 20,562 patients seeking medical care for non-cardiovascular reasons, 74,955 ECGs were performed from December 1999 to February 2001. The diagnostic criteria for Brugada-like ECG from the European Society of Cardiology were used. International Statistical Classification of Diseases codes and city residents' records were documented to indicate the reasons for visiting clinics or hospitalization and mortality outcome. Medical records were reviewed and telephone interviews were conducted. Results: Twenty-six (0.13%) of the 20,562 patients were confirmed to have Brugada-type ECGs. None of these patients had ever experienced syncope, near syncope or sudden cardiac death. After 57.1 ± 15.8 months of follow-up, there were four deaths out of the 26 patients with Brugada-type ECG (15.4%, 95% CI: 1.53-2.9%) compared with 2899 of those without (14.1%, 95% CI: 13.6-14.5%; p=0.89, log-rank test). Neither sudden cardiac death (p=0.61) nor hospitalized death (p=0.55) was different between patients with and without Brugada-type ECG. Conclusion: Patients with Brugada-type ECGs are not rare in a hospital-based population. The presence of Brugada-type ECGs in patients without syncope or sudden cardiac death was not associated with hospitalized mortality.http://www.sciencedirect.com/science/article/pii/S0929664611600351all-cause mortalityBrugada-type ECGcardiac deathsudden death
spellingShingle Jyh-Ming Jimmy Juang
Wei-Lian Phan
Pau-Chung Chen
Ling-Ping Lai
Min-Hsi Tsai
Jou-Wei Lin
Pi-Hsun Cheng
Wei-Yih Chiu
Bor-Wen Cheng
Juey-Jen Hwang
Chuen-Den Tseng
Kwan-Lih Hsu
Yung-Zu Tseng
Jiunn-Lee Lin
Fu-Tien Chiang
Brugada-Type Electrocardiogram in the Taiwanese Population–Is it a Risk Factor for Sudden Death?
Journal of the Formosan Medical Association
all-cause mortality
Brugada-type ECG
cardiac death
sudden death
title Brugada-Type Electrocardiogram in the Taiwanese Population–Is it a Risk Factor for Sudden Death?
title_full Brugada-Type Electrocardiogram in the Taiwanese Population–Is it a Risk Factor for Sudden Death?
title_fullStr Brugada-Type Electrocardiogram in the Taiwanese Population–Is it a Risk Factor for Sudden Death?
title_full_unstemmed Brugada-Type Electrocardiogram in the Taiwanese Population–Is it a Risk Factor for Sudden Death?
title_short Brugada-Type Electrocardiogram in the Taiwanese Population–Is it a Risk Factor for Sudden Death?
title_sort brugada type electrocardiogram in the taiwanese population is it a risk factor for sudden death
topic all-cause mortality
Brugada-type ECG
cardiac death
sudden death
url http://www.sciencedirect.com/science/article/pii/S0929664611600351
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