Testing of Hypothesis in Equivalence and Non Inferiority Trials-A Concept
Establishing the appropriate hypothesis is one of the important steps for carrying out the statistical tests/analysis. Its understanding is important for interpreting the results of statistical analysis. The current communication attempts to provide the concept of testing of hypothesis in non infe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/7547/17748_CE[Ra1]_F(AK)_PF1(BMAK)_PFA(AK)_PF2(PAG).pdf |
| _version_ | 1828784108024627200 |
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| author | Atul Juneja Abha R. Aggarwal Tulsi Adhikari Arvind Pandey |
| author_facet | Atul Juneja Abha R. Aggarwal Tulsi Adhikari Arvind Pandey |
| author_sort | Atul Juneja |
| collection | DOAJ |
| description | Establishing the appropriate hypothesis is one of the important steps for carrying out the statistical tests/analysis. Its understanding
is important for interpreting the results of statistical analysis. The current communication attempts to provide the concept of testing of
hypothesis in non inferiority and equivalence trials, where the null hypothesis is just reverse of what is set up for conventional superiority
trials. It is similarly looked for rejection for establishing the fact the researcher is intending to prove. It is important to mention that
equivalence or non inferiority cannot be proved by accepting the null hypothesis of no difference. Hence, establishing the appropriate
statistical hypothesis is extremely important to arrive at meaningful conclusion for the set objectives in research. |
| first_indexed | 2024-12-11T23:25:27Z |
| format | Article |
| id | doaj.art-2b3cae746aa24b669129b20460559689 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T23:25:27Z |
| publishDate | 2016-04-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-2b3cae746aa24b669129b204605596892022-12-22T00:46:13ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-04-01104LG01LG0310.7860/JCDR/2016/17748.7547Testing of Hypothesis in Equivalence and Non Inferiority Trials-A ConceptAtul Juneja0Abha R. Aggarwal1Tulsi Adhikari2Arvind Pandey3Scientist ‘D’, National Institute of Medical Statistics (ICMR), Ansari Nagar, New Delhi, India.Scientist ‘F’, National Institute of Medical Statistics (ICMR), Ansari Nagar, New Delhi, India.Scientist ‘D’, National Institute of Medical Statistics (ICMR), Ansari Nagar, New Delhi, India.Scientist ‘G’ and Director, National Institute of Medical Statistics (ICMR), Ansari Nagar, New Delhi, India.Establishing the appropriate hypothesis is one of the important steps for carrying out the statistical tests/analysis. Its understanding is important for interpreting the results of statistical analysis. The current communication attempts to provide the concept of testing of hypothesis in non inferiority and equivalence trials, where the null hypothesis is just reverse of what is set up for conventional superiority trials. It is similarly looked for rejection for establishing the fact the researcher is intending to prove. It is important to mention that equivalence or non inferiority cannot be proved by accepting the null hypothesis of no difference. Hence, establishing the appropriate statistical hypothesis is extremely important to arrive at meaningful conclusion for the set objectives in research.https://jcdr.net/articles/PDF/7547/17748_CE[Ra1]_F(AK)_PF1(BMAK)_PFA(AK)_PF2(PAG).pdfequivalence trialsstatistical hypothesis |
| spellingShingle | Atul Juneja Abha R. Aggarwal Tulsi Adhikari Arvind Pandey Testing of Hypothesis in Equivalence and Non Inferiority Trials-A Concept Journal of Clinical and Diagnostic Research equivalence trials statistical hypothesis |
| title | Testing of Hypothesis in Equivalence and Non Inferiority Trials-A Concept |
| title_full | Testing of Hypothesis in Equivalence and Non Inferiority Trials-A Concept |
| title_fullStr | Testing of Hypothesis in Equivalence and Non Inferiority Trials-A Concept |
| title_full_unstemmed | Testing of Hypothesis in Equivalence and Non Inferiority Trials-A Concept |
| title_short | Testing of Hypothesis in Equivalence and Non Inferiority Trials-A Concept |
| title_sort | testing of hypothesis in equivalence and non inferiority trials a concept |
| topic | equivalence trials statistical hypothesis |
| url | https://jcdr.net/articles/PDF/7547/17748_CE[Ra1]_F(AK)_PF1(BMAK)_PFA(AK)_PF2(PAG).pdf |
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