Modeling the quantitative specificity of DNA-binding proteins from example binding sites.

Modeling the quantitative specificity of DNA-binding proteins from example binding sites.

BACKGROUND:The binding of transcription factors to their respective DNA sites is a key component of every regulatory network. Predictions of transcription factor binding sites are usually based on models for transcription factor specificity. These models, in turn, are often based on examples of know...

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Bibliographic Details
Main Authors: Dana S F Homsi, Vineet Gupta, Gary D Stormo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2726951?pdf=render

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