Complications in Post-Liver Transplant Patients
Liver transplantation (LT) is the treatment of choice for liver failure and selected cases of malignancies. Transplantation activity has increased over the years, and indications for LT have been widened, leading to organ shortage. To face this condition, a high selection of recipients with prioriti...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/19/6173 |
| _version_ | 1797575670209970176 |
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| author | Carlotta Agostini Simone Buccianti Matteo Risaliti Laura Fortuna Luca Tirloni Rosaria Tucci Ilenia Bartolini Gian Luca Grazi |
| author_facet | Carlotta Agostini Simone Buccianti Matteo Risaliti Laura Fortuna Luca Tirloni Rosaria Tucci Ilenia Bartolini Gian Luca Grazi |
| author_sort | Carlotta Agostini |
| collection | DOAJ |
| description | Liver transplantation (LT) is the treatment of choice for liver failure and selected cases of malignancies. Transplantation activity has increased over the years, and indications for LT have been widened, leading to organ shortage. To face this condition, a high selection of recipients with prioritizing systems and an enlargement of the donor pool were necessary. Several authors published their case series reporting the results obtained with the use of marginal donors, which seem to have progressively improved over the years. The introduction of in situ and ex situ machine perfusion, although still strongly debated, and better knowledge and treatment of the complications may have a role in achieving better results. With longer survival rates, a significant number of patients will suffer from long-term complications. An extensive review of the literature concerning short- and long-term outcomes is reported trying to highlight the most recent findings. The heterogeneity of the behaviors within the different centers is evident, leading to a difficult comparison of the results and making explicit the need to obtain more consent from experts. |
| first_indexed | 2024-03-10T21:41:32Z |
| format | Article |
| id | doaj.art-2b469eef55c84f779d28e9b876a441ae |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T21:41:32Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-2b469eef55c84f779d28e9b876a441ae2023-11-19T14:35:07ZengMDPI AGJournal of Clinical Medicine2077-03832023-09-011219617310.3390/jcm12196173Complications in Post-Liver Transplant PatientsCarlotta Agostini0Simone Buccianti1Matteo Risaliti2Laura Fortuna3Luca Tirloni4Rosaria Tucci5Ilenia Bartolini6Gian Luca Grazi7Department of Experimental and Clinical Medicine, AOU Careggi, 50134 Florence, ItalyDepartment of Experimental and Clinical Medicine, AOU Careggi, 50134 Florence, ItalyDepartment of Experimental and Clinical Medicine, AOU Careggi, 50134 Florence, ItalyDepartment of Experimental and Clinical Medicine, AOU Careggi, 50134 Florence, ItalyDepartment of Experimental and Clinical Medicine, AOU Careggi, 50134 Florence, ItalyDepartment of Experimental and Clinical Medicine, AOU Careggi, 50134 Florence, ItalyDepartment of Experimental and Clinical Medicine, AOU Careggi, 50134 Florence, ItalyDepartment of Experimental and Clinical Medicine, AOU Careggi, 50134 Florence, ItalyLiver transplantation (LT) is the treatment of choice for liver failure and selected cases of malignancies. Transplantation activity has increased over the years, and indications for LT have been widened, leading to organ shortage. To face this condition, a high selection of recipients with prioritizing systems and an enlargement of the donor pool were necessary. Several authors published their case series reporting the results obtained with the use of marginal donors, which seem to have progressively improved over the years. The introduction of in situ and ex situ machine perfusion, although still strongly debated, and better knowledge and treatment of the complications may have a role in achieving better results. With longer survival rates, a significant number of patients will suffer from long-term complications. An extensive review of the literature concerning short- and long-term outcomes is reported trying to highlight the most recent findings. The heterogeneity of the behaviors within the different centers is evident, leading to a difficult comparison of the results and making explicit the need to obtain more consent from experts.https://www.mdpi.com/2077-0383/12/19/6173liver transplantationpostoperative morbiditysurgical complicationsmedical complications |
| spellingShingle | Carlotta Agostini Simone Buccianti Matteo Risaliti Laura Fortuna Luca Tirloni Rosaria Tucci Ilenia Bartolini Gian Luca Grazi Complications in Post-Liver Transplant Patients Journal of Clinical Medicine liver transplantation postoperative morbidity surgical complications medical complications |
| title | Complications in Post-Liver Transplant Patients |
| title_full | Complications in Post-Liver Transplant Patients |
| title_fullStr | Complications in Post-Liver Transplant Patients |
| title_full_unstemmed | Complications in Post-Liver Transplant Patients |
| title_short | Complications in Post-Liver Transplant Patients |
| title_sort | complications in post liver transplant patients |
| topic | liver transplantation postoperative morbidity surgical complications medical complications |
| url | https://www.mdpi.com/2077-0383/12/19/6173 |
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