Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case

Background and Objectives: Mixed Mixed Mixed germ cell tumors of the ovary, uncommon but aggressive tumors are seen most often in young women or adolescent girls, and are generally curable if found and treated early. Use of chemotherapy after initial surgery has dramatically improved the prognosis f...

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Main Authors: Ebrahimi, Khalaji Nia
Format: Article
Language:fas
Published: Qom University of Medical Sciences 2009-06-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Subjects:
Online Access:http://journal.muq.ac.ir/article-1-617-en.html
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author Ebrahimi
Khalaji Nia
author_facet Ebrahimi
Khalaji Nia
author_sort Ebrahimi
collection DOAJ
description Background and Objectives: Mixed Mixed Mixed germ cell tumors of the ovary, uncommon but aggressive tumors are seen most often in young women or adolescent girls, and are generally curable if found and treated early. Use of chemotherapy after initial surgery has dramatically improved the prognosis for many females with these tumors. This study reports a case of successful pregnancy in a patient with malignant ovarian mixed germ cell tumor. Case Report: The patient was an 18-year old nulliparous woman who had pelvic pain, menstruation delay, right Adnex mass and positive B-HCG. She was found to have a malignant mixed germ cell tumor comprising of both embryonal carcinoma and immature teratoma. Treatment consisted of salpingo-oophorectomy with adjunctive chemotherapy. In view of malignant germ cell tumors occurring almost exclusively in young females, preservation of their ovarian function and fertility was an important issue. The present study, confirmed that normal gonadal function and fertility are possible after conservative surgery for ovarian germ cell malignancies, even with adjuvant chemotherapy.
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spelling doaj.art-2b4965f002b94dbda168982b05022c9d2022-12-21T18:19:26ZfasQom University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum1735-77992008-13752009-06-01325154Malignant Ovarian Mixed Germ Cell Tumor: a Rare CaseEbrahimi0Khalaji Nia1 Qom University of Medical Sciences Qom University of Medical Sciences Background and Objectives: Mixed Mixed Mixed germ cell tumors of the ovary, uncommon but aggressive tumors are seen most often in young women or adolescent girls, and are generally curable if found and treated early. Use of chemotherapy after initial surgery has dramatically improved the prognosis for many females with these tumors. This study reports a case of successful pregnancy in a patient with malignant ovarian mixed germ cell tumor. Case Report: The patient was an 18-year old nulliparous woman who had pelvic pain, menstruation delay, right Adnex mass and positive B-HCG. She was found to have a malignant mixed germ cell tumor comprising of both embryonal carcinoma and immature teratoma. Treatment consisted of salpingo-oophorectomy with adjunctive chemotherapy. In view of malignant germ cell tumors occurring almost exclusively in young females, preservation of their ovarian function and fertility was an important issue. The present study, confirmed that normal gonadal function and fertility are possible after conservative surgery for ovarian germ cell malignancies, even with adjuvant chemotherapy.http://journal.muq.ac.ir/article-1-617-en.htmlmixed tumourmalignantneoplasmsgerm cellteratoma
spellingShingle Ebrahimi
Khalaji Nia
Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
mixed tumour
malignant
neoplasms
germ cell
teratoma
title Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case
title_full Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case
title_fullStr Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case
title_full_unstemmed Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case
title_short Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case
title_sort malignant ovarian mixed germ cell tumor a rare case
topic mixed tumour
malignant
neoplasms
germ cell
teratoma
url http://journal.muq.ac.ir/article-1-617-en.html
work_keys_str_mv AT ebrahimi malignantovarianmixedgermcelltumorararecase
AT khalajinia malignantovarianmixedgermcelltumorararecase