MiR-101-containing extracellular vesicles bind to BRD4 and enhance proliferation and migration of trophoblasts in preeclampsia

MiR-101-containing extracellular vesicles bind to BRD4 and enhance proliferation and migration of trophoblasts in preeclampsia

Abstract Background Preeclampsia (PE) is a frequently occurring pregnancy disorder in the placenta, which results in various maternal and fetal complications. The current study aims to evaluate the role of extracellular vesicles (EVs)-encapsulated microRNA (miR)-101 in biological processes of tropho...

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Bibliographic Details
Main Authors: Jinhui Cui, Xinjuan Chen, Shuo Lin, Ling Li, Jianhui Fan, Hongying Hou, Ping Li
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Stem Cell Research & Therapy
Subjects:
Preeclampsia
Extracellular vesicles
MicroRNA-101
Bromodomain-containing 4
Nuclear factor-kappa B
C-X-C motif chemokine ligand 11
Online Access:http://link.springer.com/article/10.1186/s13287-020-01720-9

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