Lipid Lowering Effect of Ethanolic Extract of Carduus crispus L. on Hypercholesterolemic Rats

The main purpose of this study was to determine possible effects of the ethanolic extract of aerial parts of Carduus crispus L. on the serum lipids in hypercholesterolemic rats. After oral administration for two weeks, C. crispus extract produced signifi cant decrease on serum total c...

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Bibliographic Details
Main Authors: G. Davaakhuu, J. Sukhdolgor, B. Gereltu
Format: Article
Language:English
Published: National University of Mongolia 2010-12-01
Series:Mongolian Journal of Biological Sciences
Subjects:
Online Access:http://mjbs.num.edu.mn/uploads/files/MJBS%20Volume%208%20Number%202%20December%202010/pdf/mjbs008-02-07.pdf
Description
Summary:The main purpose of this study was to determine possible effects of the ethanolic extract of aerial parts of Carduus crispus L. on the serum lipids in hypercholesterolemic rats. After oral administration for two weeks, C. crispus extract produced signifi cant decrease on serum total cholesterol, low density lipoprotein cholesterol, triglyceride levels and atherogenic indices in hypercholesterolemic groups (P < 0.05). C. crispus extract had no effects on serum high density lipoprotein cholesterol levels in these groups. It is concluded that the extract of aerial parts of C. crispus exhibits lipid lowering activity in hypercholesterolemic rats.
ISSN:1684-3908
2225-4994