miR-29a-3p/T-bet Regulatory Circuit Is Altered in T Cells of Patients With Hashimoto’s Thyroiditis

miR-29a-3p/T-bet Regulatory Circuit Is Altered in T Cells of Patients With Hashimoto’s Thyroiditis

ObjectiveHashimoto’s thyroiditis (HT) is a common autoimmune thyroid disorder that frequently evolves from asymptomatic, T-cell mediated chronic inflammation toward overt hypothyroidism. Previously, we have demonstrated a role for T-bet, a T helper 1/CD8+ T cell transcription factor (TF), and FoxP3,...

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Bibliographic Details
Main Authors: Stana Tokić, Mario Štefanić, Ljubica Glavaš-Obrovac, Amit Kishore, Zdenka Navratilova, Martin Petrek
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Endocrinology
Subjects:
Hashimoto disease
T-lymphocytes
hsa-miR-29a
hsa-miR-210
hsa-miR-9
disease attributes
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00264/full

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