Skin Manifestation of SARS-CoV-2: The Italian Experience
At the end of December 2019, a new coronavirus denominated Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was identified in Wuhan, Hubei province, China. Less than three months later, the World Health Organization (WHO) declared coronavirus disease-19 (COVID-19) to be a global pandemic...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/8/1566 |
| _version_ | 1797538376208875520 |
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| author | Gerardo Cazzato Caterina Foti Anna Colagrande Antonietta Cimmino Sara Scarcella Gerolamo Cicco Sara Sablone Francesca Arezzo Paolo Romita Teresa Lettini Leonardo Resta Giuseppe Ingravallo |
| author_facet | Gerardo Cazzato Caterina Foti Anna Colagrande Antonietta Cimmino Sara Scarcella Gerolamo Cicco Sara Sablone Francesca Arezzo Paolo Romita Teresa Lettini Leonardo Resta Giuseppe Ingravallo |
| author_sort | Gerardo Cazzato |
| collection | DOAJ |
| description | At the end of December 2019, a new coronavirus denominated Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was identified in Wuhan, Hubei province, China. Less than three months later, the World Health Organization (WHO) declared coronavirus disease-19 (COVID-19) to be a global pandemic. Growing numbers of clinical, histopathological, and molecular findings were subsequently reported, among which a particular interest in skin manifestations during the course of the disease was evinced. Today, about one year after the development of the first major infectious foci in Italy, various large case series of patients with COVID-19-related skin manifestations have focused on skin specimens. However, few are supported by histopathological, immunohistochemical, and polymerase chain reaction (PCR) data on skin specimens. Here, we present nine cases of COVID-positive patients, confirmed by histological, immunophenotypical, and PCR findings, who underwent skin biopsy. A review of the literature in Italian cases with COVID-related skin manifestations is then provided. |
| first_indexed | 2024-03-10T12:30:38Z |
| format | Article |
| id | doaj.art-2b5585332e2f4709bb734df12b380bcc |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T12:30:38Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-2b5585332e2f4709bb734df12b380bcc2023-11-21T14:39:21ZengMDPI AGJournal of Clinical Medicine2077-03832021-04-01108156610.3390/jcm10081566Skin Manifestation of SARS-CoV-2: The Italian ExperienceGerardo Cazzato0Caterina Foti1Anna Colagrande2Antonietta Cimmino3Sara Scarcella4Gerolamo Cicco5Sara Sablone6Francesca Arezzo7Paolo Romita8Teresa Lettini9Leonardo Resta10Giuseppe Ingravallo11Section of Pathology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Dermatology and Venereology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Pathology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Pathology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Pathology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Pathology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Forensic Medicine, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Gynecologic and Obstetrics Clinic, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Dermatology and Venereology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Pathology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Pathology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalySection of Pathology, University of Bari ‘Aldo Moro’, 70121 Bari, ItalyAt the end of December 2019, a new coronavirus denominated Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was identified in Wuhan, Hubei province, China. Less than three months later, the World Health Organization (WHO) declared coronavirus disease-19 (COVID-19) to be a global pandemic. Growing numbers of clinical, histopathological, and molecular findings were subsequently reported, among which a particular interest in skin manifestations during the course of the disease was evinced. Today, about one year after the development of the first major infectious foci in Italy, various large case series of patients with COVID-19-related skin manifestations have focused on skin specimens. However, few are supported by histopathological, immunohistochemical, and polymerase chain reaction (PCR) data on skin specimens. Here, we present nine cases of COVID-positive patients, confirmed by histological, immunophenotypical, and PCR findings, who underwent skin biopsy. A review of the literature in Italian cases with COVID-related skin manifestations is then provided.https://www.mdpi.com/2077-0383/10/8/1566SARS-CoV-2skinCOVID-19WHOItalianmanifestation |
| spellingShingle | Gerardo Cazzato Caterina Foti Anna Colagrande Antonietta Cimmino Sara Scarcella Gerolamo Cicco Sara Sablone Francesca Arezzo Paolo Romita Teresa Lettini Leonardo Resta Giuseppe Ingravallo Skin Manifestation of SARS-CoV-2: The Italian Experience Journal of Clinical Medicine SARS-CoV-2 skin COVID-19 WHO Italian manifestation |
| title | Skin Manifestation of SARS-CoV-2: The Italian Experience |
| title_full | Skin Manifestation of SARS-CoV-2: The Italian Experience |
| title_fullStr | Skin Manifestation of SARS-CoV-2: The Italian Experience |
| title_full_unstemmed | Skin Manifestation of SARS-CoV-2: The Italian Experience |
| title_short | Skin Manifestation of SARS-CoV-2: The Italian Experience |
| title_sort | skin manifestation of sars cov 2 the italian experience |
| topic | SARS-CoV-2 skin COVID-19 WHO Italian manifestation |
| url | https://www.mdpi.com/2077-0383/10/8/1566 |
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