Identification of the Toxicity Pathways Associated With Thioacetamide-Induced Injuries in Rat Liver and Kidney

Identification of the Toxicity Pathways Associated With Thioacetamide-Induced Injuries in Rat Liver and Kidney

Ingestion or exposure to chemicals poses a serious health risk. Early detection of cellular changes induced by such events is vital to identify appropriate countermeasures to prevent organ damage. We hypothesize that chemically induced organ injuries are uniquely associated with a set (module) of ge...

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Bibliographic Details
Main Authors: Patric Schyman, Richard L. Printz, Shanea K. Estes, Kelli L. Boyd, Masakazu Shiota, Anders Wallqvist
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
predictive toxicology
RNA-seq
thioacetamide
toxicogenomics
fibrosis
necrosis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01272/full

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