Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques.
Although antibody-inducing split virus vaccines (SV) are currently the most effective way to combat seasonal influenza, their efficacy can be modest, especially in immunologically-naïve individuals. We investigated immune responses towards inactivated whole influenza virus particle vaccine (WPV) for...
Main Authors: | Brendon Y Chua, Toshiki Sekiya, Marios Koutsakos, Naoki Nomura, Louise C Rowntree, Thi H O Nguyen, Hayley A McQuilten, Marumi Ohno, Yuki Ohara, Tomohiro Nishimura, Masafumi Endo, Yasushi Itoh, Jennifer R Habel, Kevin J Selva, Adam K Wheatley, Bruce D Wines, P Mark Hogarth, Stephen J Kent, Amy W Chung, David C Jackson, Lorena E Brown, Masashi Shingai, Katherine Kedzierska, Hiroshi Kida |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-10-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1010891 |
Similar Items
-
Inactivated Whole Virus Particle Influenza Vaccine Induces Anti-Neuraminidase Antibodies That May Contribute to Cross-Protection against Heterologous Virus Infection
by: Chimuka Handabile, et al.
Published: (2022-05-01) -
Immunogenicity and protective efficacy of a co-formulated two-in-one inactivated whole virus particle COVID-19/influenza vaccine
by: Chimuka Handabile, et al.
Published: (2024-02-01) -
The elucidation of plasma lipidome profiles during severe influenza in a mouse model
by: Marumi Ohno, et al.
Published: (2023-08-01) -
Selecting and Using the Appropriate Influenza Vaccine for Each Individual
by: Toshiki Sekiya, et al.
Published: (2021-05-01) -
Special Issue—Immunity to Influenza Viruses
by: Marios Koutsakos, et al.
Published: (2022-02-01)