Detecting archaic introgression and modeling multiple-wave admixture with ArchaicSeeker 2.0

Summary: ArchaicSeeker 2.0 is designed to identify the sequences derived from known or unknown archaic hominins and to further model the multiple-wave gene flows. The main functional modules involve seeking introgressed sequences, determining corresponding ancestries, and reconstructing the admixtur...

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Bibliographic Details
Main Authors: Rui Zhang, Kai Yuan, Shuhua Xu
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722001940
Description
Summary:Summary: ArchaicSeeker 2.0 is designed to identify the sequences derived from known or unknown archaic hominins and to further model the multiple-wave gene flows. The main functional modules involve seeking introgressed sequences, determining corresponding ancestries, and reconstructing the admixture history. The protocol below describes the analytic steps for the application of ArchaicSeeker 2.0 into analysis of example data of the Han Chinese population.For complete details on the use and execution of this protocol, please refer to Yuan et al. (2021).
ISSN:2666-1667