A robust ultrasensitive transcriptional switch in noisy cellular environments

Abstract Ultrasensitive transcriptional switches enable sharp transitions between transcriptional on and off states and are essential for cells to respond to environmental cues with high fidelity. However, conventional switches, which rely on direct repressor-DNA binding, are extremely noise-sensiti...

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书目详细资料
Main Authors: Eui Min Jeong, Jae Kyoung Kim
格式: 文件
语言:English
出版: Nature Portfolio 2024-03-01
丛编:npj Systems Biology and Applications
在线阅读:https://doi.org/10.1038/s41540-024-00356-2