Proteomes: A New Proteomic Journal

In the early years of proteomics, mass spectrometry served only as a technique in protein chemistry facilitating the characterization of purified proteins and mapping their posttranslational modifications (PTMs). A bit later this technique almost completely replaced Edman degradation and amino acid...

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Main Author: Jacek R. Wiśniewski
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Proteomes
Subjects:
n/a
Online Access:http://www.mdpi.com/2227-7382/1/1/1
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author Jacek R. Wiśniewski
author_facet Jacek R. Wiśniewski
author_sort Jacek R. Wiśniewski
collection DOAJ
description In the early years of proteomics, mass spectrometry served only as a technique in protein chemistry facilitating the characterization of purified proteins and mapping their posttranslational modifications (PTMs). A bit later this technique almost completely replaced Edman degradation and amino acid analysis. The continuous development of the mass spectrometry techniques created a huge analytical potential allowing the study of nearly complete proteomes in single experiments. This evolution distanced proteomics from protein chemistry and placed it in a novel position. Its capability to identify and quantify in parallel thousands of proteins and their modifications at minute sample amount requirements is one of the most fascinating technological advances in biology today.
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spelling doaj.art-2b6051fdcc5b46dc9bbf5dc69456087b2022-12-22T04:04:07ZengMDPI AGProteomes2227-73822012-10-01111210.3390/proteomes1010001Proteomes: A New Proteomic JournalJacek R. WiśniewskiIn the early years of proteomics, mass spectrometry served only as a technique in protein chemistry facilitating the characterization of purified proteins and mapping their posttranslational modifications (PTMs). A bit later this technique almost completely replaced Edman degradation and amino acid analysis. The continuous development of the mass spectrometry techniques created a huge analytical potential allowing the study of nearly complete proteomes in single experiments. This evolution distanced proteomics from protein chemistry and placed it in a novel position. Its capability to identify and quantify in parallel thousands of proteins and their modifications at minute sample amount requirements is one of the most fascinating technological advances in biology today.http://www.mdpi.com/2227-7382/1/1/1n/a
spellingShingle Jacek R. Wiśniewski
Proteomes: A New Proteomic Journal
Proteomes
n/a
title Proteomes: A New Proteomic Journal
title_full Proteomes: A New Proteomic Journal
title_fullStr Proteomes: A New Proteomic Journal
title_full_unstemmed Proteomes: A New Proteomic Journal
title_short Proteomes: A New Proteomic Journal
title_sort proteomes a new proteomic journal
topic n/a
url http://www.mdpi.com/2227-7382/1/1/1
work_keys_str_mv AT jacekrwisniewski proteomesanewproteomicjournal