Characterization in Potent Modulation on Voltage-Gated Na<sup>+</sup> Current Exerted by Deltamethrin, a Pyrethroid Insecticide

Characterization in Potent Modulation on Voltage-Gated Na<sup>+</sup> Current Exerted by Deltamethrin, a Pyrethroid Insecticide

Deltamethrin (DLT) is a type-II pyrethroid ester insecticide used in agricultural and domestic applications as well as in public health. However, transmembrane ionic channels perturbed by this compound remain largely unclear, although the agent is thought to alter the gating characteristics of volta...

Full description

Bibliographic Details
Main Authors:	Mao-Hsun Lin, Jen-Feng Lin, Meng-Cheng Yu, Sheng-Nan Wu, Chao-Liang Wu, Hsin-Yen Cho
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	International Journal of Molecular Sciences
Subjects:	pyrethroids voltage-gated Na<sup>+</sup> current late Na<sup>+</sup> current transient Na<sup>+</sup> current persistent Na<sup>+</sup> current
Online Access:	https://www.mdpi.com/1422-0067/23/23/14733

Similar Items

Inhibition of Voltage-Gated Na<sup>+</sup> Currents Exerted by KB-R7943 (2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea), an Inhibitor of Na<sup>+</sup>-Ca<sup>2+</sup> Exchanging Process
by: Sheng-Nan Wu, et al.
Published: (2023-01-01)

Characterization in Effective Stimulation on the Magnitude, Gating, Frequency Dependence, and Hysteresis of <i>I</i><sub>Na</sub> Exerted by Picaridin (or Icaridin), a Known Insect Repellent
by: Ai-Li Shiau, et al.
Published: (2022-08-01)

Characterization of Stimulatory Action on Voltage-Gated Na<sup>+</sup> Currents Caused by Omecamtiv Mecarbil, Known to Be a Myosin Activator
by: Chih-Yu Ting, et al.
Published: (2023-05-01)

Effective Modulation by Lacosamide on Cumulative Inhibition of <i>I</i><sub>Na</sub> during High-Frequency Stimulation and Recovery of <i>I</i><sub>Na</sub> Block during Conditioning Pulse Train
by: Po-Ming Wu, et al.
Published: (2022-10-01)

Zingerone Modulates Neuronal Voltage-Gated Na<sup>+</sup> and L-Type Ca<sup>2+</sup> Currents
by: Ming-Chi Lai, et al.
Published: (2022-03-01)

Characterization in Inhibitory Effectiveness of Carbamazepine in Voltage-Gated Na<sup>+</sup> and Erg-Mediated K<sup>+</sup> Currents in a Mouse Neural Crest-Derived (Neuro-2a) Cell Line
by: Po-Ming Wu, et al.
Published: (2022-07-01)

Characterization of Direct Perturbations on Voltage-Gated Sodium Current by Esaxerenone, a Nonsteroidal Mineralocorticoid Receptor Blocker
by: Wei-Ting Chang, et al.
Published: (2021-05-01)

Effectiveness of Columbianadin, a Bioactive Coumarin Derivative, in Perturbing Transient and Persistent <i>I</i><sub>Na</sub>
by: Wei-Ting Chang, et al.
Published: (2021-01-01)

Effects of Sesamin, the Major Furofuran Lignan of Sesame Oil, on the Amplitude and Gating of Voltage-Gated Na<sup>+</sup> and K<sup>+</sup> Currents
by: Ping-Chung Kuo, et al.
Published: (2020-07-01)

The Modulation of Ubiquinone, a Lipid Antioxidant, on Neuronal Voltage-Gated Sodium Current
by: Te-Yu Hung, et al.
Published: (2022-08-01)

Deficiency of Thyroid Hormone Reduces Voltage-Gated Na<sup>+</sup> Currents as Well as Expression of Na<sup>+</sup>/K<sup>+</sup>-ATPase in the Mouse Hippocampus
by: Sivaraj Mohana Sundaram, et al.
Published: (2022-04-01)

Effective Accentuation of Voltage-Gated Sodium Current Caused by Apocynin (4′-Hydroxy-3′-methoxyacetophenone), a Known NADPH-Oxidase Inhibitor
by: Tzu-Hsien Chuang, et al.
Published: (2021-09-01)

Glutamate-Evoked Ca<sup>2+</sup> Responses in the Rat Suprachiasmatic Nucleus: Involvement of Na<sup>+</sup>/K<sup>+</sup>-ATPase and Na<sup>+</sup>/Ca<sup>2+</sup>-Exchanger
by: Pi-Cheng Cheng, et al.
Published: (2023-03-01)

Activation of Voltage-Gated Na<sup>+</sup> Current by GV-58, a Known Activator of Ca<sub>V</sub> Channels
by: Hsin-Yen Cho, et al.
Published: (2022-03-01)

Inhibitory Effectiveness of Gomisin A, a Dibenzocyclooctadiene Lignan Isolated from <i>Schizandra chinensis</i>, on the Amplitude and Gating of Voltage-Gated Na<sup>+</sup> Current
by: Wei-Ting Chang, et al.
Published: (2020-11-01)

Na<sup>+</sup>,K<sup>+</sup>-ATPase with Disrupted Na<sup>+</sup> Binding Sites I and III Binds Na<sup>+</sup> with Increased Affinity at Site II and Undergoes Na<sup>+</sup>-Activated Phosphorylation with ATP
by: Hang N. Nielsen, et al.
Published: (2024-01-01)

The Evidence for Effective Inhibition of <i>I</i><sub>Na</sub> Produced by Mirogabalin ((1R,5S,6S)-6-(aminomethyl)-3-ethyl-bicyclo [3.2.0] hept-3-ene-6-acetic acid), a Known Blocker of Ca<sub>V</sub> Channels
by: Chao-Liang Wu, et al.
Published: (2022-03-01)

Cannabidiol Modulates M-Type K<sup>+</sup> and Hyperpolarization-Activated Cation Currents
by: Yen-Chin Liu, et al.
Published: (2023-09-01)

Higher Na<sup>+</sup>-Ca<sup>2+</sup> Exchanger Function and Triggered Activity Contribute to Male Predisposition to Atrial Fibrillation
by: Simon Thibault, et al.
Published: (2022-09-01)

Na<sup>+</sup> Binding and Transport: Insights from Light-Driven Na<sup>+</sup>-Pumping Rhodopsin
by: Qifan Yang, et al.
Published: (2023-10-01)

Ranolazine: An Old Drug with Emerging Potential; Lessons from Pre-Clinical and Clinical Investigations for Possible Repositioning
by: Sarah Rouhana, et al.
Published: (2021-12-01)

Effective Perturbations by Small-Molecule Modulators on Voltage-Dependent Hysteresis of Transmembrane Ionic Currents
by: Sheng-Nan Wu, et al.
Published: (2022-08-01)

Effective Perturbations by Phenobarbital on <i>I</i><sub>Na</sub>, <i>I</i><sub>K(erg)</sub>, <i>I</i><sub>K(M)</sub> and <i>I</i><sub>K(DR)</sub> during Pulse Train Stimulation in Neuroblastoma Neuro-2a Cells
by: Po-Ming Wu, et al.
Published: (2022-08-01)

Overexpression of an Inositol Phosphorylceramide Glucuronosyltransferase Gene <i>IbIPUT1</i> Inhibits Na<sup>+</sup> Uptake in Sweet Potato Roots
by: Chong Liu, et al.
Published: (2022-06-01)

The Novel Direct Modulatory Effects of Perampanel, an Antagonist of AMPA Receptors, on Voltage-Gated Sodium and M-type Potassium Currents
by: Ming-Chi Lai, et al.
Published: (2019-10-01)

The Integrated Effects of Brivaracetam, a Selective Analog of Levetiracetam, on Ionic Currents and Neuronal Excitability
by: Te-Yu Hung, et al.
Published: (2021-04-01)

Rufinamide, a Triazole-Derived Antiepileptic Drug, Stimulates Ca<sup>2+</sup>-Activated K<sup>+</sup> Currents While Inhibiting Voltage-Gated Na<sup>+</sup> Currents
by: Ming-Chi Lai, et al.
Published: (2022-11-01)

Calcium Signaling Silencing in Atrial Fibrillation: Implications for Atrial Sodium Homeostasis
by: Aaron D. Kaplan, et al.
Published: (2021-09-01)

Comparative Na<sup>+</sup> and K<sup>+</sup> Profiling Reveals Microbial Community Assembly of Alfalfa Silage in Different Saline-Alkali Soils
by: Shengnan Li, et al.
Published: (2023-09-01)

The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of <i>erg</i>-mediated K<sup>+</sup> Currents
by: Linyi Chen, et al.
Published: (2022-03-01)

Safranal Induces Vasorelaxation by Inhibiting Ca<sup>2+</sup> Influx and Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger in Isolated Rat Aortic Rings
by: Noor Nadhim Al-Saigh, et al.
Published: (2022-06-01)

The effect of saponins from <it>Ampelozizyphus amazonicus</it> Ducke on the renal Na<sup>+</sup> pumps’ activities and urinary excretion of natriuretic peptides
by: Diniz Lúcio Ricardo, et al.
Published: (2012-04-01)

Late Na<sup>+</sup> Current Is [Ca<sup>2+</sup>]<sub>i</sub>-Dependent in Canine Ventricular Myocytes
by: Dénes Kiss, et al.
Published: (2021-11-01)

Antiarrhythmic and Inotropic Effects of Selective Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger Inhibition: What Can We Learn from the Pharmacological Studies?
by: Norbert Nagy, et al.
Published: (2022-11-01)

Effect of Cell Cycle on Cell Surface Expression of Voltage-Gated Sodium Channels and Na<sup>+</sup>,K<sup>+</sup>-ATPase
by: Samantha Edenfield, et al.
Published: (2022-10-01)

In Vitro Cell Sensitivity to Palytoxin Correlates with High Gene Expression of the Na<sup>+</sup>/K<sup>+</sup>-ATPase β2 Subunit Isoform
by: Marco Pelin, et al.
Published: (2020-08-01)

Interaction of (+)-Strebloside and Its Derivatives with Na<sup>+</sup>/K<sup>+</sup>-ATPase and Other Targets
by: Yulin Ren, et al.
Published: (2021-09-01)

Dual Mechanisms of Cardiac Action Potential Prolongation by 4-Oxo-Nonenal Increasing the Risk of Arrhythmia; Late Na<sup>+</sup> Current Induction and hERG K<sup>+</sup> Channel Inhibition
by: Seong-Woo Choi, et al.
Published: (2021-07-01)

Structural Insights into the Interactions of Digoxin and Na<sup>+</sup>/K<sup>+</sup>-ATPase and Other Targets for the Inhibition of Cancer Cell Proliferation
by: Yulin Ren, et al.
Published: (2021-06-01)

Salt-Stress-Induced Ion Transport Contributes to K<sup>+</sup>/Na<sup>+</sup> Homeostasis in Roots of Ping’ou Hybrid Hazelnut
by: Da Luo, et al.
Published: (2023-08-01)