Advances in Artificial Intelligence-Assisted Coronary Computed Tomographic Angiography for Atherosclerotic Plaque Characterization

Coronary artery disease is a leading cause of death worldwide. Major adverse cardiac events are associated not only with coronary luminal stenosis but also with atherosclerotic plaque components. Coronary computed tomography angiography (CCTA) enables non-invasive evaluation of atherosclerotic plaqu...

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Main Authors: Qian Chen, Fan Zhou, Guanghui Xie, Chun Xiang Tang, Xiaofei Gao, Yamei Zhang, Xindao Yin, Hui Xu, Long Jiang Zhang
Format: Article
Language:English
Published: IMR Press 2024-01-01
Series:Reviews in Cardiovascular Medicine
Subjects:
Online Access:https://www.imrpress.com/journal/RCM/25/1/10.31083/j.rcm2501027
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author Qian Chen
Fan Zhou
Guanghui Xie
Chun Xiang Tang
Xiaofei Gao
Yamei Zhang
Xindao Yin
Hui Xu
Long Jiang Zhang
author_facet Qian Chen
Fan Zhou
Guanghui Xie
Chun Xiang Tang
Xiaofei Gao
Yamei Zhang
Xindao Yin
Hui Xu
Long Jiang Zhang
author_sort Qian Chen
collection DOAJ
description Coronary artery disease is a leading cause of death worldwide. Major adverse cardiac events are associated not only with coronary luminal stenosis but also with atherosclerotic plaque components. Coronary computed tomography angiography (CCTA) enables non-invasive evaluation of atherosclerotic plaque along the entire coronary tree. However, precise and efficient assessment of plaque features on CCTA is still a challenge for physicians in daily practice. Artificial intelligence (AI) refers to algorithms that can simulate intelligent human behavior to improve clinical work efficiency. Recently, cardiovascular imaging has seen remarkable advancements with the use of AI. AI-assisted CCTA has the potential to facilitate the clinical workflow, offer objective and repeatable quantitative results, accelerate the interpretation of reports, and guide subsequent treatment. Several AI algorithms have been developed to provide a comprehensive assessment of atherosclerotic plaques. This review serves to highlight the cutting-edge applications of AI-assisted CCTA in atherosclerosis plaque characterization, including detecting obstructive plaques, assessing plaque volumes and vulnerability, monitoring plaque progression, and providing risk assessment. Finally, this paper discusses the current problems and future directions for implementing AI in real-world clinical settings.
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spelling doaj.art-2b610d32c06845ccbef83d647893639e2024-01-31T01:12:56ZengIMR PressReviews in Cardiovascular Medicine1530-65502024-01-012512710.31083/j.rcm2501027S1530-6550(23)01143-2Advances in Artificial Intelligence-Assisted Coronary Computed Tomographic Angiography for Atherosclerotic Plaque CharacterizationQian Chen0Fan Zhou1Guanghui Xie2Chun Xiang Tang3Xiaofei Gao4Yamei Zhang5Xindao Yin6Hui Xu7Long Jiang Zhang8Department of Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, Jiangsu, ChinaDepartment of Radiology, Jinling Hospital, Medical School of Nanjing University, 210002 Nanjing, Jiangsu, ChinaDepartment of Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, Jiangsu, ChinaDepartment of Radiology, Jinling Hospital, Medical School of Nanjing University, 210002 Nanjing, Jiangsu, ChinaDepartment of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, Jiangsu, ChinaDepartment of Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, Jiangsu, ChinaDepartment of Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, Jiangsu, ChinaDepartment of Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, Jiangsu, ChinaDepartment of Radiology, Jinling Hospital, Medical School of Nanjing University, 210002 Nanjing, Jiangsu, ChinaCoronary artery disease is a leading cause of death worldwide. Major adverse cardiac events are associated not only with coronary luminal stenosis but also with atherosclerotic plaque components. Coronary computed tomography angiography (CCTA) enables non-invasive evaluation of atherosclerotic plaque along the entire coronary tree. However, precise and efficient assessment of plaque features on CCTA is still a challenge for physicians in daily practice. Artificial intelligence (AI) refers to algorithms that can simulate intelligent human behavior to improve clinical work efficiency. Recently, cardiovascular imaging has seen remarkable advancements with the use of AI. AI-assisted CCTA has the potential to facilitate the clinical workflow, offer objective and repeatable quantitative results, accelerate the interpretation of reports, and guide subsequent treatment. Several AI algorithms have been developed to provide a comprehensive assessment of atherosclerotic plaques. This review serves to highlight the cutting-edge applications of AI-assisted CCTA in atherosclerosis plaque characterization, including detecting obstructive plaques, assessing plaque volumes and vulnerability, monitoring plaque progression, and providing risk assessment. Finally, this paper discusses the current problems and future directions for implementing AI in real-world clinical settings.https://www.imrpress.com/journal/RCM/25/1/10.31083/j.rcm2501027artificial intelligencecoronary ct angiographycoronary plaquedeep learning
spellingShingle Qian Chen
Fan Zhou
Guanghui Xie
Chun Xiang Tang
Xiaofei Gao
Yamei Zhang
Xindao Yin
Hui Xu
Long Jiang Zhang
Advances in Artificial Intelligence-Assisted Coronary Computed Tomographic Angiography for Atherosclerotic Plaque Characterization
Reviews in Cardiovascular Medicine
artificial intelligence
coronary ct angiography
coronary plaque
deep learning
title Advances in Artificial Intelligence-Assisted Coronary Computed Tomographic Angiography for Atherosclerotic Plaque Characterization
title_full Advances in Artificial Intelligence-Assisted Coronary Computed Tomographic Angiography for Atherosclerotic Plaque Characterization
title_fullStr Advances in Artificial Intelligence-Assisted Coronary Computed Tomographic Angiography for Atherosclerotic Plaque Characterization
title_full_unstemmed Advances in Artificial Intelligence-Assisted Coronary Computed Tomographic Angiography for Atherosclerotic Plaque Characterization
title_short Advances in Artificial Intelligence-Assisted Coronary Computed Tomographic Angiography for Atherosclerotic Plaque Characterization
title_sort advances in artificial intelligence assisted coronary computed tomographic angiography for atherosclerotic plaque characterization
topic artificial intelligence
coronary ct angiography
coronary plaque
deep learning
url https://www.imrpress.com/journal/RCM/25/1/10.31083/j.rcm2501027
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