Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis
Sialylation catalyzed by sialyltransferases is one of the most interesting enzymatic glycosyl transfer reactions, since chemical sialylations usually give only low yields and lead to poor stereoselectivities. In the last decade, several bacterial sialyltransferases were identified and foun...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
2006-04-01
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| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://chimia.ch/chimia/article/view/4156 |
| _version_ | 1811320303881551872 |
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| author | Oliver Schwardt Tamara Visekruna Said Rabbani Beat Ernst |
| author_facet | Oliver Schwardt Tamara Visekruna Said Rabbani Beat Ernst |
| author_sort | Oliver Schwardt |
| collection | DOAJ |
| description |
Sialylation catalyzed by sialyltransferases is one of the most interesting enzymatic glycosyl transfer reactions, since chemical sialylations usually give only low yields and lead to poor stereoselectivities. In the last decade, several bacterial sialyltransferases were identified and
found to exhibit broader substrate specificity than their mammalian counterparts. This suggests the potential usefulness of bacterial sialyltransferases in chemo-enzymatic synthesis of natural and non-natural sialooligosaccharides.
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| first_indexed | 2024-04-13T12:57:27Z |
| format | Article |
| id | doaj.art-2b6287ef1c7c4e9c93c34373f34dbeac |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-04-13T12:57:27Z |
| publishDate | 2006-04-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-2b6287ef1c7c4e9c93c34373f34dbeac2022-12-22T02:46:01ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242006-04-0160410.2533/000942906777674787Minireview: Bacterial Sialyltransferases for Carbohydrate SynthesisOliver SchwardtTamara VisekrunaSaid RabbaniBeat Ernst Sialylation catalyzed by sialyltransferases is one of the most interesting enzymatic glycosyl transfer reactions, since chemical sialylations usually give only low yields and lead to poor stereoselectivities. In the last decade, several bacterial sialyltransferases were identified and found to exhibit broader substrate specificity than their mammalian counterparts. This suggests the potential usefulness of bacterial sialyltransferases in chemo-enzymatic synthesis of natural and non-natural sialooligosaccharides. https://chimia.ch/chimia/article/view/4156Bacterial sialyltransferaseChemo-enzymatic synthesisSubstrate specificity |
| spellingShingle | Oliver Schwardt Tamara Visekruna Said Rabbani Beat Ernst Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis CHIMIA Bacterial sialyltransferase Chemo-enzymatic synthesis Substrate specificity |
| title | Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis |
| title_full | Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis |
| title_fullStr | Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis |
| title_full_unstemmed | Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis |
| title_short | Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis |
| title_sort | minireview bacterial sialyltransferases for carbohydrate synthesis |
| topic | Bacterial sialyltransferase Chemo-enzymatic synthesis Substrate specificity |
| url | https://chimia.ch/chimia/article/view/4156 |
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