Antibacterial zwitterionic hydrogel for flexible and wearable ultrafast-response strain sensors with low hysteresis
Zwitterionic hydrogels, with their unique antibacterial and tissue-adhesive nature, show great potential in the fields of wearable sensors, healthcare monitoring, and e-skins. However, it remains a huge challenge to integrate high elasticity and low hysteresis in such a hydrogel via simple methods....
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-03-01
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| Series: | Giant |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666542523000966 |
| _version_ | 1797248263576879104 |
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| author | Haihua Wang Leixin Meng Yanan Ye Jingheng Wu Shilei Zhu Yushan Liu Ke Li Xin Yang Meng Wei Mengxi Wang Ling Song Shuaijun Guo |
| author_facet | Haihua Wang Leixin Meng Yanan Ye Jingheng Wu Shilei Zhu Yushan Liu Ke Li Xin Yang Meng Wei Mengxi Wang Ling Song Shuaijun Guo |
| author_sort | Haihua Wang |
| collection | DOAJ |
| description | Zwitterionic hydrogels, with their unique antibacterial and tissue-adhesive nature, show great potential in the fields of wearable sensors, healthcare monitoring, and e-skins. However, it remains a huge challenge to integrate high elasticity and low hysteresis in such a hydrogel via simple methods. Herein, a novel tissue-adhesive zwitterionic hydrogel sensor was fabricated by a simple one-pot method using copolymerization of [2-(Methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide (SBMA), N-[Tris (hydroxymethyl)methyl] acrylamide (THMA), and acrylic acid (AA), which was crosslinked by polyethylene glycol diglycidyl ether (PEGDE), a crosslinker famous for its low-toxicity and biocompatibility. The obtained SAT hydrogel shows robust elasticity with low hysteresis and fatigue resistance, which is essential for the long-term use. The introduction of THMA and PAA enhances the adhesive strength and reversible resilience of the hydrogel by interfacial hydrogen bonding, resulting in superior adhesion to skin without causing harm. The chemical crosslinker existing in SAT hydrogel enables it to withstand large deformations while maintaining stability. Besides the well-known antibacterial properties, the addition of SBMA enables the hydrogel to exhibit excellent electrical properties and a rapid response (19.5 ms) within a wide strain-sensing range, which facilitates accurate detection of various human body motions, such as joint bending, swallowing, and heartbeats. Moreover, the hydrogel demonstrates biocompatibility and excellent antibacterial activity, promising a safer and more comfortable experience for users. |
| first_indexed | 2024-03-08T16:50:49Z |
| format | Article |
| id | doaj.art-2b641d72a36a4cfbbf1dc06b6776907b |
| institution | Directory Open Access Journal |
| issn | 2666-5425 |
| language | English |
| last_indexed | 2024-04-24T20:11:49Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Giant |
| spelling | doaj.art-2b641d72a36a4cfbbf1dc06b6776907b2024-03-23T06:26:10ZengElsevierGiant2666-54252024-03-0117100234Antibacterial zwitterionic hydrogel for flexible and wearable ultrafast-response strain sensors with low hysteresisHaihua Wang0Leixin Meng1Yanan Ye2Jingheng Wu3Shilei Zhu4Yushan Liu5Ke Li6Xin Yang7Meng Wei8Mengxi Wang9Ling Song10Shuaijun Guo11Shaanxi Key Laboratory of Chemical Additives for Industry, Xi'an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science and Technology, Xuefu Road, Weiyang district, Xi'an, 710021, China; Corresponding authors.Shaanxi Key Laboratory of Chemical Additives for Industry, Xi'an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science and Technology, Xuefu Road, Weiyang district, Xi'an, 710021, ChinaCollege of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China; Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering, Taiyuan, 030024, China; Corresponding authors.Department of Hand Surgery, Beijing Jishuitan Hospital, Beijing, 100035, China; Corresponding authors.College of Physics, Taiyuan University of Technology, Taiyuan, 030024, ChinaShaanxi Key Laboratory of Chemical Additives for Industry, Xi'an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science and Technology, Xuefu Road, Weiyang district, Xi'an, 710021, ChinaXi'an Key Laboratory for Prevention and Treatment of Common Aging Diseases, Translational and Research Centre for Prevention and Therapy of Chronic Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, 710021, ChinaShaanxi Key Laboratory of Chemical Additives for Industry, Xi'an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science and Technology, Xuefu Road, Weiyang district, Xi'an, 710021, ChinaShaanxi Key Laboratory of Chemical Additives for Industry, Xi'an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science and Technology, Xuefu Road, Weiyang district, Xi'an, 710021, ChinaShaanxi Key Laboratory of Chemical Additives for Industry, Xi'an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science and Technology, Xuefu Road, Weiyang district, Xi'an, 710021, ChinaShaanxi Key Laboratory of Chemical Additives for Industry, Xi'an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science and Technology, Xuefu Road, Weiyang district, Xi'an, 710021, ChinaCollege of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, ChinaZwitterionic hydrogels, with their unique antibacterial and tissue-adhesive nature, show great potential in the fields of wearable sensors, healthcare monitoring, and e-skins. However, it remains a huge challenge to integrate high elasticity and low hysteresis in such a hydrogel via simple methods. Herein, a novel tissue-adhesive zwitterionic hydrogel sensor was fabricated by a simple one-pot method using copolymerization of [2-(Methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide (SBMA), N-[Tris (hydroxymethyl)methyl] acrylamide (THMA), and acrylic acid (AA), which was crosslinked by polyethylene glycol diglycidyl ether (PEGDE), a crosslinker famous for its low-toxicity and biocompatibility. The obtained SAT hydrogel shows robust elasticity with low hysteresis and fatigue resistance, which is essential for the long-term use. The introduction of THMA and PAA enhances the adhesive strength and reversible resilience of the hydrogel by interfacial hydrogen bonding, resulting in superior adhesion to skin without causing harm. The chemical crosslinker existing in SAT hydrogel enables it to withstand large deformations while maintaining stability. Besides the well-known antibacterial properties, the addition of SBMA enables the hydrogel to exhibit excellent electrical properties and a rapid response (19.5 ms) within a wide strain-sensing range, which facilitates accurate detection of various human body motions, such as joint bending, swallowing, and heartbeats. Moreover, the hydrogel demonstrates biocompatibility and excellent antibacterial activity, promising a safer and more comfortable experience for users.http://www.sciencedirect.com/science/article/pii/S2666542523000966Zwitterionic hydrogelLow hysteresisAntibacterial activityRapid responseWearable sensor |
| spellingShingle | Haihua Wang Leixin Meng Yanan Ye Jingheng Wu Shilei Zhu Yushan Liu Ke Li Xin Yang Meng Wei Mengxi Wang Ling Song Shuaijun Guo Antibacterial zwitterionic hydrogel for flexible and wearable ultrafast-response strain sensors with low hysteresis Giant Zwitterionic hydrogel Low hysteresis Antibacterial activity Rapid response Wearable sensor |
| title | Antibacterial zwitterionic hydrogel for flexible and wearable ultrafast-response strain sensors with low hysteresis |
| title_full | Antibacterial zwitterionic hydrogel for flexible and wearable ultrafast-response strain sensors with low hysteresis |
| title_fullStr | Antibacterial zwitterionic hydrogel for flexible and wearable ultrafast-response strain sensors with low hysteresis |
| title_full_unstemmed | Antibacterial zwitterionic hydrogel for flexible and wearable ultrafast-response strain sensors with low hysteresis |
| title_short | Antibacterial zwitterionic hydrogel for flexible and wearable ultrafast-response strain sensors with low hysteresis |
| title_sort | antibacterial zwitterionic hydrogel for flexible and wearable ultrafast response strain sensors with low hysteresis |
| topic | Zwitterionic hydrogel Low hysteresis Antibacterial activity Rapid response Wearable sensor |
| url | http://www.sciencedirect.com/science/article/pii/S2666542523000966 |
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