Biological Activities of Scolopendrid Pharmacopuncture
2Reactive Oxygen Species(ROS) are continuously produced at a high rate as a by- product of aerobic metabolism. Since tissue damage by free radical increases with age, the reactive oxygen species(ROS) such as hydrogen peroxide(H2O2), nitric oxide(NO). Several lines of evidence provided that ROS appea...
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| Format: | Article |
| Language: | English |
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Korean Pharmacopuncture Institute
2010-09-01
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| Series: | Journal of Pharmacopuncture |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3831/KPI.2010.13.3.005 |
| _version_ | 1811282561165426688 |
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| author | Kim Sung-Chul Seo Geun-young Lee sung-Won Park Sung-Joo Kim Jae-Hyo Ahn Seong-Hun Hwang Sung-Yeoun |
| author_facet | Kim Sung-Chul Seo Geun-young Lee sung-Won Park Sung-Joo Kim Jae-Hyo Ahn Seong-Hun Hwang Sung-Yeoun |
| author_sort | Kim Sung-Chul |
| collection | DOAJ |
| description | 2Reactive Oxygen Species(ROS) are continuously produced at a high rate as a by- product of aerobic metabolism. Since tissue damage by free radical increases with age, the reactive oxygen species(ROS) such as hydrogen peroxide(H2O2), nitric oxide(NO). Several lines of evidence provided that ROS appears to cause to develop aging-related various diseases such as cancer, arthritis, cardiovascular disease.
Our reserch objective was to examine the in vitro biological activity of Scolopendrid Pharmacopuncture, including the total poly-phenol content, DPPH radical scavenging, ABTS radical scavenging, Superoxide dismutase(SOD)-like activity, Nitrite scavenging ability.
The total poly-phenol contents of Scolopendrid Pharmacopuncture was 35.859mg/L. Elctron donation ability on DPPH was 36.82%. The 2,2'-azinobis-3-ehtlbezothiazoline-6- sulfonic acid radical decolorization (ABTS) was 84.7%. The superoxide dismutase (SOD)-like activities of Scolopendrid Pharmacopuncture was 44.33%. The nitrite scavenging effects were pH dependent, and were highest at pH 1.5(45.2%) and lowest at pH 6.0(11.3%). We conclude that Scolopendrid Pharmacopuncture may be useful as potential sources of antioxidant. |
| first_indexed | 2024-04-13T01:54:49Z |
| format | Article |
| id | doaj.art-2b65adb52a4b4b9d9e47972608792cb2 |
| institution | Directory Open Access Journal |
| issn | 2093-6966 2234-6856 |
| language | English |
| last_indexed | 2024-04-13T01:54:49Z |
| publishDate | 2010-09-01 |
| publisher | Korean Pharmacopuncture Institute |
| record_format | Article |
| series | Journal of Pharmacopuncture |
| spelling | doaj.art-2b65adb52a4b4b9d9e47972608792cb22022-12-22T03:07:47ZengKorean Pharmacopuncture InstituteJournal of Pharmacopuncture2093-69662234-68562010-09-0113351310.3831/KPI.2010.13.3.005 Biological Activities of Scolopendrid PharmacopunctureKim Sung-Chul 0Seo Geun-young 1Lee sung-Won 2Park Sung-Joo 3Kim Jae-Hyo 4Ahn Seong-Hun 5Hwang Sung-Yeoun 6Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang UniversityDept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University, Korea Bio Medical Science institueDept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University, Korea Bio Medical Science institueDept. of herbology, school of Oriental Medicine, Wonkwang UniversityDept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University, Korea Bio Medical Science institueDept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University, Korea Bio Medical Science institueKorea Bio Medical Science institue2Reactive Oxygen Species(ROS) are continuously produced at a high rate as a by- product of aerobic metabolism. Since tissue damage by free radical increases with age, the reactive oxygen species(ROS) such as hydrogen peroxide(H2O2), nitric oxide(NO). Several lines of evidence provided that ROS appears to cause to develop aging-related various diseases such as cancer, arthritis, cardiovascular disease. Our reserch objective was to examine the in vitro biological activity of Scolopendrid Pharmacopuncture, including the total poly-phenol content, DPPH radical scavenging, ABTS radical scavenging, Superoxide dismutase(SOD)-like activity, Nitrite scavenging ability. The total poly-phenol contents of Scolopendrid Pharmacopuncture was 35.859mg/L. Elctron donation ability on DPPH was 36.82%. The 2,2'-azinobis-3-ehtlbezothiazoline-6- sulfonic acid radical decolorization (ABTS) was 84.7%. The superoxide dismutase (SOD)-like activities of Scolopendrid Pharmacopuncture was 44.33%. The nitrite scavenging effects were pH dependent, and were highest at pH 1.5(45.2%) and lowest at pH 6.0(11.3%). We conclude that Scolopendrid Pharmacopuncture may be useful as potential sources of antioxidant.http://dx.doi.org/10.3831/KPI.2010.13.3.005Scolopendrid Pharmacopuncturenitrite scavenging abilitySOD-like activityantioxidant activity |
| spellingShingle | Kim Sung-Chul Seo Geun-young Lee sung-Won Park Sung-Joo Kim Jae-Hyo Ahn Seong-Hun Hwang Sung-Yeoun Biological Activities of Scolopendrid Pharmacopuncture Journal of Pharmacopuncture Scolopendrid Pharmacopuncture nitrite scavenging ability SOD-like activity antioxidant activity |
| title | Biological Activities of Scolopendrid Pharmacopuncture |
| title_full | Biological Activities of Scolopendrid Pharmacopuncture |
| title_fullStr | Biological Activities of Scolopendrid Pharmacopuncture |
| title_full_unstemmed | Biological Activities of Scolopendrid Pharmacopuncture |
| title_short | Biological Activities of Scolopendrid Pharmacopuncture |
| title_sort | biological activities of scolopendrid pharmacopuncture |
| topic | Scolopendrid Pharmacopuncture nitrite scavenging ability SOD-like activity antioxidant activity |
| url | http://dx.doi.org/10.3831/KPI.2010.13.3.005 |
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