p66Shc gene expression in peripheral blood mononuclear cells and progression of diabetic complications

p66Shc gene expression in peripheral blood mononuclear cells and progression of diabetic complications

Abstract Background The risk of diabetic complications is modified by genetic and epigenetic factors. p66Shc drives the hyperglycaemic cell damage and its deletion prevents experimental diabetic complications. We herein tested whether p66Shc expression in peripheral blood mononuclear cells (PBMCs) p...

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Bibliographic Details
Main Authors: Gian Paolo Fadini, Mattia Albiero, Benedetta Maria Bonora, Nicol Poncina, Saula Vigili de Kreutzenberg, Angelo Avogaro
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Cardiovascular Diabetology
Subjects:
Aging
Oxidative stress
Longevity
Risk assessment
Online Access:http://link.springer.com/article/10.1186/s12933-018-0660-9

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