Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra

The present study was aimed to evaluate the phytochemical screening and antimicrobial activity of the petroleum ether and methanol extracts from the mature leaves of Richardia scabra from India. Disc diffusion method was used to determine the zone inhibition of the tested samples for antibacterial a...

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Main Authors: Kathirvel Poonkodi, Subban Ravi
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2016-03-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:https://www.banglajol.info/index.php/BJP/article/view/24666
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author Kathirvel Poonkodi
Subban Ravi
author_facet Kathirvel Poonkodi
Subban Ravi
author_sort Kathirvel Poonkodi
collection DOAJ
description The present study was aimed to evaluate the phytochemical screening and antimicrobial activity of the petroleum ether and methanol extracts from the mature leaves of Richardia scabra from India. Disc diffusion method was used to determine the zone inhibition of the tested samples for antibacterial and agar plug method was used to determine the antifungal activity, while the microtube-dilution technique was used to determine the minimum inhibitory concentration. Both extracts showed significant antibacterial and antifungal activities when tested against 10 bacterial and four fungal strains. The minimum inhibitory concentrations of the methanol extract of R. scabra ranged between 12.5100 ?g/mL for bacterial strains. Alkaloids, steroids, flavonoids, fatty acids, terpenoids and simple sugar were detected as phytoconstituents of extracts. To the best of our knowledge, this is the first report against antimicrobial activity of common weed species R. scabra found in India.
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spelling doaj.art-2b6cdd3179eb4b6ba05676fc7172015f2022-12-21T20:46:02ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882016-03-0111210.3329/bjp.v11i2.24666Phytochemical investigation and in vitro antimicrobial activity of Richardia scabraKathirvel Poonkodi0Subban Ravi1Department of Chemistry, Nallamuthu GounderMahalingam College, Pollachi 641001Department of Chemistry, Karpagam University, Coimbatore 21, TamilnaduThe present study was aimed to evaluate the phytochemical screening and antimicrobial activity of the petroleum ether and methanol extracts from the mature leaves of Richardia scabra from India. Disc diffusion method was used to determine the zone inhibition of the tested samples for antibacterial and agar plug method was used to determine the antifungal activity, while the microtube-dilution technique was used to determine the minimum inhibitory concentration. Both extracts showed significant antibacterial and antifungal activities when tested against 10 bacterial and four fungal strains. The minimum inhibitory concentrations of the methanol extract of R. scabra ranged between 12.5100 ?g/mL for bacterial strains. Alkaloids, steroids, flavonoids, fatty acids, terpenoids and simple sugar were detected as phytoconstituents of extracts. To the best of our knowledge, this is the first report against antimicrobial activity of common weed species R. scabra found in India.https://www.banglajol.info/index.php/BJP/article/view/24666AntimicrobialRichardia scabra
spellingShingle Kathirvel Poonkodi
Subban Ravi
Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra
Bangladesh Journal of Pharmacology
Antimicrobial
Richardia scabra
title Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra
title_full Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra
title_fullStr Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra
title_full_unstemmed Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra
title_short Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra
title_sort phytochemical investigation and in vitro antimicrobial activity of richardia scabra
topic Antimicrobial
Richardia scabra
url https://www.banglajol.info/index.php/BJP/article/view/24666
work_keys_str_mv AT kathirvelpoonkodi phytochemicalinvestigationandinvitroantimicrobialactivityofrichardiascabra
AT subbanravi phytochemicalinvestigationandinvitroantimicrobialactivityofrichardiascabra