Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra
The present study was aimed to evaluate the phytochemical screening and antimicrobial activity of the petroleum ether and methanol extracts from the mature leaves of Richardia scabra from India. Disc diffusion method was used to determine the zone inhibition of the tested samples for antibacterial a...
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Format: | Article |
Language: | English |
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Bangladesh Pharmacological Society
2016-03-01
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Series: | Bangladesh Journal of Pharmacology |
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Online Access: | https://www.banglajol.info/index.php/BJP/article/view/24666 |
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author | Kathirvel Poonkodi Subban Ravi |
author_facet | Kathirvel Poonkodi Subban Ravi |
author_sort | Kathirvel Poonkodi |
collection | DOAJ |
description | The present study was aimed to evaluate the phytochemical screening and antimicrobial activity of the petroleum ether and methanol extracts from the mature leaves of Richardia scabra from India. Disc diffusion method was used to determine the zone inhibition of the tested samples for antibacterial and agar plug method was used to determine the antifungal activity, while the microtube-dilution technique was used to determine the minimum inhibitory concentration. Both extracts showed significant antibacterial and antifungal activities when tested against 10 bacterial and four fungal strains. The minimum inhibitory concentrations of the methanol extract of R. scabra ranged between 12.5100 ?g/mL for bacterial strains. Alkaloids, steroids, flavonoids, fatty acids, terpenoids and simple sugar were detected as phytoconstituents of extracts. To the best of our knowledge, this is the first report against antimicrobial activity of common weed species R. scabra found in India. |
first_indexed | 2024-12-19T00:11:25Z |
format | Article |
id | doaj.art-2b6cdd3179eb4b6ba05676fc7172015f |
institution | Directory Open Access Journal |
issn | 1991-0088 |
language | English |
last_indexed | 2024-12-19T00:11:25Z |
publishDate | 2016-03-01 |
publisher | Bangladesh Pharmacological Society |
record_format | Article |
series | Bangladesh Journal of Pharmacology |
spelling | doaj.art-2b6cdd3179eb4b6ba05676fc7172015f2022-12-21T20:46:02ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882016-03-0111210.3329/bjp.v11i2.24666Phytochemical investigation and in vitro antimicrobial activity of Richardia scabraKathirvel Poonkodi0Subban Ravi1Department of Chemistry, Nallamuthu GounderMahalingam College, Pollachi 641001Department of Chemistry, Karpagam University, Coimbatore 21, TamilnaduThe present study was aimed to evaluate the phytochemical screening and antimicrobial activity of the petroleum ether and methanol extracts from the mature leaves of Richardia scabra from India. Disc diffusion method was used to determine the zone inhibition of the tested samples for antibacterial and agar plug method was used to determine the antifungal activity, while the microtube-dilution technique was used to determine the minimum inhibitory concentration. Both extracts showed significant antibacterial and antifungal activities when tested against 10 bacterial and four fungal strains. The minimum inhibitory concentrations of the methanol extract of R. scabra ranged between 12.5100 ?g/mL for bacterial strains. Alkaloids, steroids, flavonoids, fatty acids, terpenoids and simple sugar were detected as phytoconstituents of extracts. To the best of our knowledge, this is the first report against antimicrobial activity of common weed species R. scabra found in India.https://www.banglajol.info/index.php/BJP/article/view/24666AntimicrobialRichardia scabra |
spellingShingle | Kathirvel Poonkodi Subban Ravi Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra Bangladesh Journal of Pharmacology Antimicrobial Richardia scabra |
title | Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra |
title_full | Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra |
title_fullStr | Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra |
title_full_unstemmed | Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra |
title_short | Phytochemical investigation and in vitro antimicrobial activity of Richardia scabra |
title_sort | phytochemical investigation and in vitro antimicrobial activity of richardia scabra |
topic | Antimicrobial Richardia scabra |
url | https://www.banglajol.info/index.php/BJP/article/view/24666 |
work_keys_str_mv | AT kathirvelpoonkodi phytochemicalinvestigationandinvitroantimicrobialactivityofrichardiascabra AT subbanravi phytochemicalinvestigationandinvitroantimicrobialactivityofrichardiascabra |