Cardiomyocyte Marker Expression in Mouse Embryonic Fibroblasts by Cell-Free Cardiomyocyte Extract and Epigenetic Manipulation

Cardiomyocyte Marker Expression in Mouse Embryonic Fibroblasts by Cell-Free Cardiomyocyte Extract and Epigenetic Manipulation

Background: The regenerative capacity of the mammalian heart is quite limited. Recent reports have focused on reprogramming mesenchymal stem cells into cardiomyocytes. We investigated whether fibroblasts could transdifferentiate into myocardium. Methods: Mouse embryonic fibroblasts were treated wit...

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Bibliographic Details
Main Authors: Tahereh Talaei-Khozani, Fatemeh Heidari, Tahereh Esmaeilpour, Zahra Vojdani, Zohrah Mostafavi-Pour, Leili Rohani
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2014-03-01
Series:Iranian Journal of Medical Sciences
Subjects:
Cardiomyocytes
Cell transdifferentiation
Histone deacetylase inhibitors
Fibroblast
Online Access:http://ijms.sums.ac.ir/index.php/IJMS/article/view/645

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