Interaction between COX-1 and COX-2 increases susceptibility to ischemic stroke in a Chinese population

Interaction between COX-1 and COX-2 increases susceptibility to ischemic stroke in a Chinese population

Abstract Background Mutations of cyclooxygenase gene (COX gene) may increase the susceptibility of ischemic stroke. We investigated five variants (rs5788, rs1330344, rs3842788, rs20417, and rs689466) of two COX genes in order to explaining the association between these polymorphisms and we also inve...

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Bibliographic Details
Main Authors: Lei Zhao, Jinghuan Fang, Muke Zhou, Jie Zhou, Lihua Yu, Ning Chen, Li He
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Neurology
Subjects:
Ischemic stroke
COX-1
COX-2
Single nucleotide polymorphism
Gene-gene
Interaction
Online Access:http://link.springer.com/article/10.1186/s12883-019-1505-1

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