Influence of Formulation Factors, Process Parameters, and Selected Quality Attributes on Carvedilol Release from Roller-Compacted Hypromellose-Based Matrix Tablets

Influence of Formulation Factors, Process Parameters, and Selected Quality Attributes on Carvedilol Release from Roller-Compacted Hypromellose-Based Matrix Tablets

The importance of roller compaction is recently increasing. This study evaluates the combined effects of formulation factors, process parameters, and selected quality attributes on drug release from roller-compacted hypromellose-based matrix tablets containing carvedilol as a model drug. The influen...

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Bibliographic Details
Main Authors: Aleša Dular Vovko, Bor Hodžić, Tina Brec, Grega Hudovornik, Franc Vrečer
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
roller compaction
hypromellose
matrix tablets
drug release
spatial filtering technique
Online Access:https://www.mdpi.com/1999-4923/14/4/876

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