Rapid-onset dystonia-parkinsonism is associated with reduced cerebral blood flow without gray matter changes

Rapid-onset dystonia-parkinsonism is associated with reduced cerebral blood flow without gray matter changes

PurposePrevious research showed discrete neuropathological changes associated with rapid-onset dystonia-parkinsonism (RDP) in brains from patients with an ATP1A3 variant, specifically in areas that mediate motor function. The purpose of this study was to determine if magnetic resonance imaging metho...

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Bibliographic Details
Main Authors: Christopher T. Whitlow, Kyle M. Atcheson, Beverly M. Snively, Jared F. Cook, Jeongchul Kim, Ihtsham U. Haq, Kathleen J. Sweadner, Laurie J. Ozelius, Allison Brashear
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Neurology
Subjects:
voxel-based morphometry
rapid-onset dystonia-parkinsonism (RDP)
ATP1A3
cerebral blood flow (CBF)
arterial spin labeling
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1116723/full

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