Hypoxia causes trophoblast cell ferroptosis to induce miscarriage through lnc-HZ06/HIF1α-SUMO/NCOA4 axis
Defects of human trophoblast cells may induce miscarriage (abnormal early embryo loss), which is generally regulated by lncRNAs. Ferroptosis is a newly identified iron-dependent programmed cell death. Hypoxia is an important and unavoidable feature in mammalian cells. However, whether hypoxia might...
Main Authors: | Peng Tian, Zhongyan Xu, Jiarong Guo, Jingsong Zhao, Weina Chen, Wenxin Huang, Manli Wang, Chenyang Mi, Ying Zhang, Yang Yang, Huidong Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-04-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231724000491 |
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