Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"?
<p>Abstract</p> <p>Objective</p> <p>Liver injury due to trauma is a rare indication for transplantation. The main indications in such cases were uncontrollable bleeding and insufficient hepatic function. Because of poor results, liver transplantation in these patients i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2010-04-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | http://www.eurjmedres.com/content/15/4/169 |
| _version_ | 1818276053696643072 |
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| author | Heuer M Kaiser GM Lendemans S Vernadakis S Treckmann JW Paul A |
| author_facet | Heuer M Kaiser GM Lendemans S Vernadakis S Treckmann JW Paul A |
| author_sort | Heuer M |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Objective</p> <p>Liver injury due to trauma is a rare indication for transplantation. The main indications in such cases were uncontrollable bleeding and insufficient hepatic function. Because of poor results, liver transplantation in these patients is occasionally described as "waste of organs", however based on insufficient data. This study aims to report our experience and to critically question the indication of transplantation in these patients.</p> <p>Methods</p> <p>All liver transplantations at our institution were reviewed retrospectively. This covered 1,529 liver transplants between September 1987 and December 2008. Of them, 6 transplants were performed due to motor-vehicle accidents which caused uncontrollable acute liver trauma in 4 patients. The patients' peri-operative course, short- and long-term outcomes were analyzed.</p> <p>Results</p> <p>Five deceased-donor liver transplantations (4 full size, 1 split) and 1 living donor (right) transplantation were performed. The median GCS score was 9/15; the median MELD score was 15. Postoperative complications were observed in 3 patients, requiring re-operation in 2. After a median (range) follow-up of 32.95 (10.3-55.6) months, 2 patients are alive and remain well on immunosuppression.</p> <p>Conclusion</p> <p>Liver transplantation in patients with otherwise surgically uncontrollable acute liver injury can be indicated as a life saving procedure and can be performed successfully in highly selected cases.</p> |
| first_indexed | 2024-12-12T22:39:32Z |
| format | Article |
| id | doaj.art-2b773d40bc4b40d08e50df8367400173 |
| institution | Directory Open Access Journal |
| issn | 2047-783X |
| language | English |
| last_indexed | 2024-12-12T22:39:32Z |
| publishDate | 2010-04-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj.art-2b773d40bc4b40d08e50df83674001732022-12-22T00:09:21ZengBMCEuropean Journal of Medical Research2047-783X2010-04-0115416910.1186/2047-783X-15-4-169Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"?Heuer MKaiser GMLendemans SVernadakis STreckmann JWPaul A<p>Abstract</p> <p>Objective</p> <p>Liver injury due to trauma is a rare indication for transplantation. The main indications in such cases were uncontrollable bleeding and insufficient hepatic function. Because of poor results, liver transplantation in these patients is occasionally described as "waste of organs", however based on insufficient data. This study aims to report our experience and to critically question the indication of transplantation in these patients.</p> <p>Methods</p> <p>All liver transplantations at our institution were reviewed retrospectively. This covered 1,529 liver transplants between September 1987 and December 2008. Of them, 6 transplants were performed due to motor-vehicle accidents which caused uncontrollable acute liver trauma in 4 patients. The patients' peri-operative course, short- and long-term outcomes were analyzed.</p> <p>Results</p> <p>Five deceased-donor liver transplantations (4 full size, 1 split) and 1 living donor (right) transplantation were performed. The median GCS score was 9/15; the median MELD score was 15. Postoperative complications were observed in 3 patients, requiring re-operation in 2. After a median (range) follow-up of 32.95 (10.3-55.6) months, 2 patients are alive and remain well on immunosuppression.</p> <p>Conclusion</p> <p>Liver transplantation in patients with otherwise surgically uncontrollable acute liver injury can be indicated as a life saving procedure and can be performed successfully in highly selected cases.</p>http://www.eurjmedres.com/content/15/4/169abdominal traumaliver injuryliver transplantationprognosis"waste of organs" |
| spellingShingle | Heuer M Kaiser GM Lendemans S Vernadakis S Treckmann JW Paul A Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"? European Journal of Medical Research abdominal trauma liver injury liver transplantation prognosis "waste of organs" |
| title | Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"? |
| title_full | Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"? |
| title_fullStr | Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"? |
| title_full_unstemmed | Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"? |
| title_short | Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"? |
| title_sort | transplantation after blunt trauma to the liver a valuable option or just a waste of organs |
| topic | abdominal trauma liver injury liver transplantation prognosis "waste of organs" |
| url | http://www.eurjmedres.com/content/15/4/169 |
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