Blood M2-like Monocyte Polarization Is Associated with Calcific Plaque Phenotype in Stable Coronary Artery Disease: A Sub-Study of SMARTool Clinical Trial

Blood M2-like Monocyte Polarization Is Associated with Calcific Plaque Phenotype in Stable Coronary Artery Disease: A Sub-Study of SMARTool Clinical Trial

Background: Atherosclerosis is a chronic inflammatory disease. The balance between pro- and anti-inflammatory factors, acting on the arterial wall, promotes less or more coronary plaque macro-calcification, respectively. We investigated the association between monocyte phenotypic polarization and CT...

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Bibliographic Details
Main Authors: Silverio Sbrana, Antonella Cecchettini, Luca Bastiani, Nicoletta Di Giorgi, Annamaria Mazzone, Elisa Ceccherini, Federico Vozzi, Chiara Caselli, Danilo Neglia, Alberto Clemente, Arthur J. H. A. Scholte, Oberdan Parodi, Gualtiero Pelosi, Silvia Rocchiccioli
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
coronary artery disease
blood monocyte subsets
flow cytometry
plasma cytokines
coronary CT angiography
plaque calcium volume
Online Access:https://www.mdpi.com/2227-9059/10/3/565

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