Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10
Background: Cryptosporidium is a protozoan parasite with worldwide distribution. The aim of this study was to estimate the prevalence of Cryptosporidium infection by antigen detection in faeces among immunocompromised patients referred to educational hospitals of Ahvaz City, South-West of Iran, 2009...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2010-12-01
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| Series: | Iranian Journal of Parasitology |
| Subjects: | |
| Online Access: | http://journals.tums.ac.ir/upload_files/pdf/17283.pdf |
| _version_ | 1831586814559780864 |
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| author | A Balouty Dehkordy A Rafiei SM Alavi SM Latifi |
| author_facet | A Balouty Dehkordy A Rafiei SM Alavi SM Latifi |
| author_sort | A Balouty Dehkordy |
| collection | DOAJ |
| description | Background: Cryptosporidium is a protozoan parasite with worldwide distribution. The aim of this study was to estimate the prevalence of Cryptosporidium infection by antigen detection in faeces among immunocompromised patients referred to educational hospitals of Ahvaz City, South-West of Iran, 2009-2010.Methods: Fecal samples from 176 immunocompromised patients were collected and Cryptosporidium coproantigen test was performed using ELISA method (DRG kit, Germany). A questionnaire was completed for each case and the results were analyzed using descriptive and Chi-Square tests, by SPSS statistical software (15th version).Results: Our study indicated 5.1% Cryptosporidium infection prevalence in the immunocompromised participated population. Furthermore, 4.2 %, 4%, 4.5 % and 9.1% infection rates were identified in children suffered from hematopoietic malignancy, adult cancer patients, renal transplant recipients, and HIV+ cases, respectively. There was not significant correlation between the infection and age and gender (P>0.05). Infection was most frequent among HIV+ patients.Conclusion: The present study confirmed the high prevalence of Cryptosporidium antigen in fecal samples of immunocompromised patients in the region. As no chemotherapeutic agents have yet proven, especially in immunosuppressed patients, therefore our results highlight the importance of preventive intervention in these groups. |
| first_indexed | 2024-12-17T21:43:33Z |
| format | Article |
| id | doaj.art-2b7d1c57b612411b81572ce73d4b287f |
| institution | Directory Open Access Journal |
| issn | 1735-7020 2008-238X |
| language | English |
| last_indexed | 2024-12-17T21:43:33Z |
| publishDate | 2010-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Parasitology |
| spelling | doaj.art-2b7d1c57b612411b81572ce73d4b287f2022-12-21T21:31:31ZengTehran University of Medical SciencesIranian Journal of Parasitology1735-70202008-238X2010-12-0154447Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10A Balouty DehkordyA RafieiSM AlaviSM LatifiBackground: Cryptosporidium is a protozoan parasite with worldwide distribution. The aim of this study was to estimate the prevalence of Cryptosporidium infection by antigen detection in faeces among immunocompromised patients referred to educational hospitals of Ahvaz City, South-West of Iran, 2009-2010.Methods: Fecal samples from 176 immunocompromised patients were collected and Cryptosporidium coproantigen test was performed using ELISA method (DRG kit, Germany). A questionnaire was completed for each case and the results were analyzed using descriptive and Chi-Square tests, by SPSS statistical software (15th version).Results: Our study indicated 5.1% Cryptosporidium infection prevalence in the immunocompromised participated population. Furthermore, 4.2 %, 4%, 4.5 % and 9.1% infection rates were identified in children suffered from hematopoietic malignancy, adult cancer patients, renal transplant recipients, and HIV+ cases, respectively. There was not significant correlation between the infection and age and gender (P>0.05). Infection was most frequent among HIV+ patients.Conclusion: The present study confirmed the high prevalence of Cryptosporidium antigen in fecal samples of immunocompromised patients in the region. As no chemotherapeutic agents have yet proven, especially in immunosuppressed patients, therefore our results highlight the importance of preventive intervention in these groups.http://journals.tums.ac.ir/upload_files/pdf/17283.pdfCryptosporidiumCoproantigenImmunocompromised PatientsELISAHumanIran |
| spellingShingle | A Balouty Dehkordy A Rafiei SM Alavi SM Latifi Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10 Iranian Journal of Parasitology Cryptosporidium Coproantigen Immunocompromised Patients ELISA Human Iran |
| title | Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10 |
| title_full | Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10 |
| title_fullStr | Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10 |
| title_full_unstemmed | Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10 |
| title_short | Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10 |
| title_sort | prevalence of cryptosporidium infection in immunocompromised pa tients in south west of iran 2009 10 |
| topic | Cryptosporidium Coproantigen Immunocompromised Patients ELISA Human Iran |
| url | http://journals.tums.ac.ir/upload_files/pdf/17283.pdf |
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