A brief overview on the applications of hyaluronic acid in periodontal therapy

Hyaluronic acid (HA) is a component of the extracellular matrix of the non-mineralized and mineralized tissues, including the periodontium. HA have important physiological and biological properties. HA maintains the tissue volume, presents bacteriostatic, anti-inflammatory, osteoinductive, and angio...

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Main Authors: Andrada Soanca, Vlad Mastica, Emoke Pall, Alexandra Roman, Andreea Ciurea, Diana Onet, Iulia Cristina Micu, Darian Rusu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2022-12-01
Series:Romanian Journal of Stomatology
Subjects:
Online Access:https://rjs.com.ro/articles/2022.4/RJS_2022_4_Art-06.pdf
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author Andrada Soanca
Vlad Mastica
Emoke Pall
Alexandra Roman
Andreea Ciurea
Diana Onet
Iulia Cristina Micu
Darian Rusu
author_facet Andrada Soanca
Vlad Mastica
Emoke Pall
Alexandra Roman
Andreea Ciurea
Diana Onet
Iulia Cristina Micu
Darian Rusu
author_sort Andrada Soanca
collection DOAJ
description Hyaluronic acid (HA) is a component of the extracellular matrix of the non-mineralized and mineralized tissues, including the periodontium. HA have important physiological and biological properties. HA maintains the tissue volume, presents bacteriostatic, anti-inflammatory, osteoinductive, and angiogenetic properties, as well as stimulates many cell functions having a role in wound healing. HA has been used as an adjunctive in the treatment of gingivitis, periodontitis, gingival recessions, or in the reconstruction of papilla deficiencies. In periodontitis patients, the association of HA with subgingival mechanical instrumentation reduces local inflammation and its use with access flap results in larger attachment level gain of infrabony defects compared to control groups non treated with HA. HA application in conjunction with advanced flaps may improve gingival recession levels. HA injection for papillary deficiency seems to be a viable treatment option that improves clinical volume, esthetic outcomes and is associated with minimal pain.
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spelling doaj.art-2b82d307670945ec945213095203c3792023-09-12T09:36:40ZengAmaltea Medical Publishing HouseRomanian Journal of Stomatology1843-08052069-60782022-12-0168418819210.37897/RJS.2022.4.6A brief overview on the applications of hyaluronic acid in periodontal therapyAndrada Soanca0Vlad Mastica1Emoke Pall2Alexandra Roman3Andreea Ciurea4Diana Onet5Iulia Cristina Micu6Darian Rusu7Department of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Veterinary Reproduction, Obstetrics and Gynecology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, “Anton Sculean” Research Center of Periodontal and Peri-implant Diseases, Faculty of Dental Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaHyaluronic acid (HA) is a component of the extracellular matrix of the non-mineralized and mineralized tissues, including the periodontium. HA have important physiological and biological properties. HA maintains the tissue volume, presents bacteriostatic, anti-inflammatory, osteoinductive, and angiogenetic properties, as well as stimulates many cell functions having a role in wound healing. HA has been used as an adjunctive in the treatment of gingivitis, periodontitis, gingival recessions, or in the reconstruction of papilla deficiencies. In periodontitis patients, the association of HA with subgingival mechanical instrumentation reduces local inflammation and its use with access flap results in larger attachment level gain of infrabony defects compared to control groups non treated with HA. HA application in conjunction with advanced flaps may improve gingival recession levels. HA injection for papillary deficiency seems to be a viable treatment option that improves clinical volume, esthetic outcomes and is associated with minimal pain. https://rjs.com.ro/articles/2022.4/RJS_2022_4_Art-06.pdfhyaluronic acidperiodontitisperiodontal therapyregeneration
spellingShingle Andrada Soanca
Vlad Mastica
Emoke Pall
Alexandra Roman
Andreea Ciurea
Diana Onet
Iulia Cristina Micu
Darian Rusu
A brief overview on the applications of hyaluronic acid in periodontal therapy
Romanian Journal of Stomatology
hyaluronic acid
periodontitis
periodontal therapy
regeneration
title A brief overview on the applications of hyaluronic acid in periodontal therapy
title_full A brief overview on the applications of hyaluronic acid in periodontal therapy
title_fullStr A brief overview on the applications of hyaluronic acid in periodontal therapy
title_full_unstemmed A brief overview on the applications of hyaluronic acid in periodontal therapy
title_short A brief overview on the applications of hyaluronic acid in periodontal therapy
title_sort brief overview on the applications of hyaluronic acid in periodontal therapy
topic hyaluronic acid
periodontitis
periodontal therapy
regeneration
url https://rjs.com.ro/articles/2022.4/RJS_2022_4_Art-06.pdf
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