A brief overview on the applications of hyaluronic acid in periodontal therapy
Hyaluronic acid (HA) is a component of the extracellular matrix of the non-mineralized and mineralized tissues, including the periodontium. HA have important physiological and biological properties. HA maintains the tissue volume, presents bacteriostatic, anti-inflammatory, osteoinductive, and angio...
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Format: | Article |
Language: | English |
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Amaltea Medical Publishing House
2022-12-01
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Series: | Romanian Journal of Stomatology |
Subjects: | |
Online Access: | https://rjs.com.ro/articles/2022.4/RJS_2022_4_Art-06.pdf |
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author | Andrada Soanca Vlad Mastica Emoke Pall Alexandra Roman Andreea Ciurea Diana Onet Iulia Cristina Micu Darian Rusu |
author_facet | Andrada Soanca Vlad Mastica Emoke Pall Alexandra Roman Andreea Ciurea Diana Onet Iulia Cristina Micu Darian Rusu |
author_sort | Andrada Soanca |
collection | DOAJ |
description | Hyaluronic acid (HA) is a component of the extracellular matrix of the non-mineralized and mineralized tissues, including the periodontium. HA have important physiological and biological properties. HA maintains the tissue volume, presents bacteriostatic, anti-inflammatory, osteoinductive, and angiogenetic properties, as well as stimulates many cell functions having a role in wound healing. HA has been used as an adjunctive in the treatment of gingivitis, periodontitis, gingival recessions, or in the reconstruction of papilla deficiencies. In periodontitis patients, the association of HA with subgingival mechanical instrumentation reduces local inflammation and its use with access flap results in larger attachment level gain of infrabony defects compared to control groups non treated with HA. HA application in conjunction with advanced flaps may improve gingival recession levels. HA injection for papillary deficiency seems to be a viable treatment option that improves clinical volume, esthetic outcomes and is associated with minimal pain. |
first_indexed | 2024-03-12T01:28:06Z |
format | Article |
id | doaj.art-2b82d307670945ec945213095203c379 |
institution | Directory Open Access Journal |
issn | 1843-0805 2069-6078 |
language | English |
last_indexed | 2024-03-12T01:28:06Z |
publishDate | 2022-12-01 |
publisher | Amaltea Medical Publishing House |
record_format | Article |
series | Romanian Journal of Stomatology |
spelling | doaj.art-2b82d307670945ec945213095203c3792023-09-12T09:36:40ZengAmaltea Medical Publishing HouseRomanian Journal of Stomatology1843-08052069-60782022-12-0168418819210.37897/RJS.2022.4.6A brief overview on the applications of hyaluronic acid in periodontal therapyAndrada Soanca0Vlad Mastica1Emoke Pall2Alexandra Roman3Andreea Ciurea4Diana Onet5Iulia Cristina Micu6Darian Rusu7Department of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Veterinary Reproduction, Obstetrics and Gynecology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Periodontology, “Anton Sculean” Research Center of Periodontal and Peri-implant Diseases, Faculty of Dental Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaHyaluronic acid (HA) is a component of the extracellular matrix of the non-mineralized and mineralized tissues, including the periodontium. HA have important physiological and biological properties. HA maintains the tissue volume, presents bacteriostatic, anti-inflammatory, osteoinductive, and angiogenetic properties, as well as stimulates many cell functions having a role in wound healing. HA has been used as an adjunctive in the treatment of gingivitis, periodontitis, gingival recessions, or in the reconstruction of papilla deficiencies. In periodontitis patients, the association of HA with subgingival mechanical instrumentation reduces local inflammation and its use with access flap results in larger attachment level gain of infrabony defects compared to control groups non treated with HA. HA application in conjunction with advanced flaps may improve gingival recession levels. HA injection for papillary deficiency seems to be a viable treatment option that improves clinical volume, esthetic outcomes and is associated with minimal pain. https://rjs.com.ro/articles/2022.4/RJS_2022_4_Art-06.pdfhyaluronic acidperiodontitisperiodontal therapyregeneration |
spellingShingle | Andrada Soanca Vlad Mastica Emoke Pall Alexandra Roman Andreea Ciurea Diana Onet Iulia Cristina Micu Darian Rusu A brief overview on the applications of hyaluronic acid in periodontal therapy Romanian Journal of Stomatology hyaluronic acid periodontitis periodontal therapy regeneration |
title | A brief overview on the applications of hyaluronic acid in periodontal therapy |
title_full | A brief overview on the applications of hyaluronic acid in periodontal therapy |
title_fullStr | A brief overview on the applications of hyaluronic acid in periodontal therapy |
title_full_unstemmed | A brief overview on the applications of hyaluronic acid in periodontal therapy |
title_short | A brief overview on the applications of hyaluronic acid in periodontal therapy |
title_sort | brief overview on the applications of hyaluronic acid in periodontal therapy |
topic | hyaluronic acid periodontitis periodontal therapy regeneration |
url | https://rjs.com.ro/articles/2022.4/RJS_2022_4_Art-06.pdf |
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